术后牙痛——抗炎和镇痛药物的比较研究
Postoperative dental pain--a comparative study of anti-inflammatory and analgesic agents.
作者信息
Campbell W I, Kendrick R W
机构信息
Ulster Hospital, Dundonald, Belfast.
出版信息
Ulster Med J. 1991 Apr;60(1):39-43.
Abstract
Intravenous dexamethasone and diclofenac were evaluated in a double blind randomised trial, relative to an opioid (pentazocine) and placebo (saline), in 160 patients undergoing extraction of impacted lower third molar teeth. Test drugs were administered intravenously before surgery to provide postoperative analgesia. Following the operation, pain was assessed using a 10 cm visual analogue scale. Patients who received diclofenac reported significantly less pain than others 30 minutes after surgery (p less than 0.05). Pain scores on the day following surgery were also significantly lower in the diclofenac group compared to the opioid and placebo groups (p less than 0.05) but not less than those who received dexamethasone--possibly indicating a long term advantage of the anti-inflammatory drugs. Vomiting was a problem in the opioid group.
摘要
在一项双盲随机试验中，对160例接受拔除下颌阻生第三磨牙手术的患者，评估了静脉注射地塞米松和双氯芬酸相对于一种阿片类药物（喷他佐辛）和安慰剂（生理盐水）的效果。术前静脉注射试验药物以提供术后镇痛。术后，使用10厘米视觉模拟量表评估疼痛程度。接受双氯芬酸治疗的患者在术后30分钟报告的疼痛明显少于其他患者（p<0.05）。与阿片类药物组和安慰剂组相比，双氯芬酸组术后第一天的疼痛评分也显著更低（p<0.05），但不比接受地塞米松的患者低——这可能表明抗炎药物具有长期优势。呕吐是阿片类药物组的一个问题。
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本文引用的文献
1
Nausea and vomiting.恶心与呕吐。
Br J Anaesth. 1984 Jan;56(1):19-27. doi: 10.1093/bja/56.1.19.
2
Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine.与安慰剂、对乙酰氨基酚以及对乙酰氨基酚加可待因相比，术前给予布洛芬对术后疼痛的抑制作用。
J Clin Pharmacol. 1983 Jan;23(1):37-43. doi: 10.1002/j.1552-4604.1983.tb02702.x.
3
Effects of anti-inflammatory drugs on prostaglandin biosynthesis.抗炎药物对前列腺素生物合成的影响。
Nat New Biol. 1972 Jul 26;238(82):104-6. doi: 10.1038/newbio238104a0.
4
Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs.前列腺素与阿司匹林类药物产生镇痛作用的机制。
Br J Pharmacol. 1973 Sep;49(1):86-97. doi: 10.1111/j.1476-5381.1973.tb08270.x.
5
Steroids and postoperative analgesia.类固醇与术后镇痛。
Anaesth Intensive Care. 1985 Nov;13(4):395-8. doi: 10.1177/0310057X8501300412.
6
Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium.重症监护病房患者的退热治疗：低剂量双氯芬酸钠的评估
Intensive Care Med. 1986;12(5):370-3. doi: 10.1007/BF00292928.
7
The anti-inflammatory effects of dexamethasone and therapeutic ultrasound in oral surgery.
Br J Oral Maxillofac Surg. 1985 Feb;23(1):17-23. doi: 10.1016/0266-4356(85)90074-9.
8
Venous sequelae following i.v. administration of diclofenac.静脉注射双氯芬酸后的静脉后遗症。
Br J Anaesth. 1989 May;62(5):545-7. doi: 10.1093/bja/62.5.545.
9
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10
The hyperalgesic effects of prostacyclin and prostaglandin E2.前列环素和前列腺素E2的痛觉过敏作用。
Prostaglandins. 1978 Jul;16(1):31-7. doi: 10.1016/0090-6980(78)90199-5.
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