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实验性缺血性止血带疼痛会延迟健康志愿者半固体食物的胃排空。

Experimental ischaemic tourniquet pain delays gastric emptying of semi-solids in healthy volunteers.

作者信息

Petring O U, Sloth Madsen P

机构信息

Department of Anaesthesia, Rigshospitalet, Copenhagen, Denmark.

出版信息

Acta Anaesthesiol Scand. 1991 May;35(4):293-6. doi: 10.1111/j.1399-6576.1991.tb03292.x.

DOI:10.1111/j.1399-6576.1991.tb03292.x
PMID:1853689
Abstract

The effect of controlled, experimental ischaemic pain, induced by tourniquet, on gastric emptying of a semi-solid meal of Tc-99m labelled Chelex-100 resin oatmeal was assessed in seven healthy volunteers, each acting as his/her own control. In the pain study, the submaximal effort tourniquet test was applied immediately, 30 min and 45 min after beginning of the study. Pain intensity was rated during the procedure using a linear visual analogue scale (VAS). All subjects participating in the study assessed their pain as close to maximal tolerance after 2-4 min. The pain stimulus caused an immediate acceleration, followed by a reproducible, significant delay in gastric emptying relative to the control situation. The median reduction in meal emptied after 60 min in the pain study was 15% P = 0.035). There was no difference in the duration of the lag period between the groups.

摘要

通过止血带诱导的可控性实验性缺血性疼痛对7名健康志愿者(每人作为自己的对照)摄入的99m锝标记的Chelex - 100树脂燕麦片半固体餐胃排空的影响进行了评估。在疼痛研究中,在研究开始后立即、30分钟和45分钟应用次最大强度的止血带测试。在操作过程中使用线性视觉模拟量表(VAS)对疼痛强度进行评分。所有参与研究的受试者在2 - 4分钟后将他们的疼痛评估为接近最大耐受程度。疼痛刺激导致胃排空立即加速,随后相对于对照情况出现可重复的、显著延迟。疼痛研究中60分钟后排空餐量的中位数减少了15%(P = 0.035)。两组之间延迟期的持续时间没有差异。

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