酚妥拉明对健康志愿者基础状态及哌替啶诱导的胃排空抑制的影响。
The effect of phentolamine on basal and pethidine-induced inhibition of gastric emptying in healthy volunteers.
作者信息
Petring O U
机构信息
Department of Anaesthesia, Rigshospitalet, Copenhagen, Denmark.
出版信息
Br J Clin Pharmacol. 1989 Oct;28(4):409-13. doi: 10.1111/j.1365-2125.1989.tb03520.x.
Abstract
- The effect of phentolamine 5 mg i.v. on basal and pethidine-induced inhibition of gastric emptying of semisolid TC-99m labelled Chelex-100 resin/oatmeal was studied in ten healthy volunteers. 2. Each volunteer acted as his/her own control. 3. Basal gastric emptying remained unchanged after administration of phentolamine. 4. Administration of phentolamine reversed the pethidine-induced inhibition of gastric emptying.
摘要
- 在10名健康志愿者中研究了静脉注射5毫克酚妥拉明对基础状态以及哌替啶诱导的半固体99m锝标记的螯合树脂/燕麦片胃排空抑制的影响。2. 每名志愿者均作为自身对照。3. 注射酚妥拉明后基础胃排空未发生变化。4. 注射酚妥拉明逆转了哌替啶诱导的胃排空抑制。
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