Ross Danielle S, Victor Marcia, Sumartojo Esther, Cannon Michael J
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
J Womens Health (Larchmt). 2008 Jun;17(5):849-58. doi: 10.1089/jwh.2007.0523.
Congenital cytomegalovirus (CMV) is as common a cause of serious disability as Down syndrome and neural tube defects. When acquired prior to or during pregnancy, CMV can be transmitted transplacentally to the fetus, sometimes causing serious temporary symptoms, permanent disabilities, or both to the child. One way to prevent infection before and during pregnancy is through simple hygienic practices, such as handwashing.
This study used the 2005 annual HealthStyles survey, a mail survey of the U.S. population aged <18 years, to assess knowledge of congenital CMV. Self-reports by female respondents measured willingness to adopt particular hygienic behaviors to prevent CMV transmission.
Only 14% of female respondents had heard of CMV. Among women who reported they had heard of CMV, the largest proportion said they had heard about it from a doctor, hospital, clinic, or other health professional (29%). The accuracy of women's knowledge of what conditions congenital CMV can cause in the fetus was limited. The prevention behaviors surveyed in the present study (i.e., handwashing, not sharing drinking glasses or eating utensils with young children, and not kissing young children on the mouth) appeared to be generally acceptable.
There are prevention behaviors that have the potential of substantially reducing the occurrence of CMV-related permanent disability in children. However, our results suggest that few women are aware of CMV or these prevention behaviors.
先天性巨细胞病毒(CMV)是导致严重残疾的常见病因,与唐氏综合征和神经管缺陷一样普遍。在妊娠前或妊娠期间感染CMV时,它可经胎盘传播给胎儿,有时会导致儿童出现严重的暂时症状、永久性残疾或两者皆有。在妊娠前和妊娠期间预防感染的一种方法是通过简单的卫生习惯,如洗手。
本研究使用了2005年年度健康生活方式调查,这是一项针对18岁以下美国人群的邮寄调查,以评估对先天性CMV的了解情况。女性受访者的自我报告衡量了她们采取特定卫生行为以预防CMV传播的意愿。
只有14%的女性受访者听说过CMV。在报告听说过CMV的女性中,最大比例的人表示他们是从医生、医院、诊所或其他卫生专业人员那里听说的(29%)。女性对先天性CMV可导致胎儿出现何种状况的了解准确性有限。本研究中调查的预防行为(即洗手、不与幼儿共用水杯或餐具、不亲吻幼儿嘴巴)似乎普遍可以接受。
存在一些预防行为,有可能大幅减少儿童中与CMV相关的永久性残疾的发生。然而,我们的结果表明,很少有女性了解CMV或这些预防行为。