汽车修理喷漆工和汽车修理工的红细胞体积增加。
Increased erythrocyte volume in car repair painters and car mechanics.
作者信息
Beving H, Tornling G, Olsson P
机构信息
Department of Experimental Surgery, Thoracic Clinics, Stockholm, Sweden.
出版信息
Br J Ind Med. 1991 Jul;48(7):499-501. doi: 10.1136/oem.48.7.499.
The biological effect of occupational long term low level exposure to organic solvents was studied in 17 car repair painters and 28 car mechanics, and compared with a control group consisting of 46 healthy men not exposed to organic solvents. The erythrocyte count (RBC) was significantly decreased for both the painters and the mechanics compared with the control group, and a significant increase in the mean erythrocyte volume (MCV) was seen in painters. The mode in size distribution of the erythrocytes (MAXRBC) was shifted towards larger cell volumes for both painters and mechanics. When data from painters and mechanics were combined, the exposed group showed a significantly reduced erythrocyte count (RBC), an increased mean erythrocyte volume (MVC), and an increased mean platelet volume (MPV) compared with the controls. Exposure measurements in combination with analysis of haematological parameters may be a tool for early detection of cellular changes in the blood caused by exposure to solvents, before the appearance of clinical symptoms.
对17名汽车修理喷漆工和28名汽车修理工进行了研究，以探讨职业性长期低水平接触有机溶剂的生物学效应，并与由46名未接触有机溶剂的健康男性组成的对照组进行比较。与对照组相比，喷漆工和修理工的红细胞计数（RBC）均显著降低，喷漆工的平均红细胞体积（MCV）显著增加。喷漆工和修理工的红细胞大小分布模式（MAXRBC）均向更大的细胞体积偏移。当将喷漆工和修理工的数据合并时，与对照组相比，暴露组的红细胞计数（RBC）显著降低，平均红细胞体积（MVC）增加，平均血小板体积（MPV）增加。将接触测量与血液学参数分析相结合，可能是在临床症状出现之前早期检测因接触溶剂导致血液中细胞变化的一种工具。
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