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本文引用的文献

1
Exposure to organic solvents. A cross-sectional epidemiologic investigation on occupationally exposed care and industrial spray painters with special reference to the nervous system.有机溶剂暴露。一项针对职业暴露的护理人员和工业喷漆工的横断面流行病学调查，特别关注神经系统。
Scand J Work Environ Health. 1980 Dec;6(4):239-73. doi: 10.5271/sjweh.2609.
2
Increased uptake of serotonin in platelets from car painters occupationally exposed to mixtures of solvents and organic isocyanates.职业性接触溶剂和有机异氰酸酯混合物的汽车喷漆工血小板中血清素摄取增加。
Scand J Work Environ Health. 1983 Jun;9(3):253-8. doi: 10.5271/sjweh.2412.
3
Effect on the uptake kinetics of serotonin (5-hydroxytryptamine) in platelets from workers with long-term exposure to organic solvents. A pilot study.长期接触有机溶剂的工人血小板中血清素（5-羟色胺）摄取动力学的影响。一项初步研究。
Scand J Work Environ Health. 1984 Aug;10(4):229-34. doi: 10.5271/sjweh.2337.
4
A health survey of car painters of different ethnic origin and the importance of racial factors.不同种族出身汽车喷漆工的健康调查及种族因素的重要性。
J Soc Occup Med. 1984 Aug;34(3):86-9. doi: 10.1093/occmed/34.3.86.
5
Car painters' exposure to a mixture of organic solvents. Serum activities of liver enzymes.汽车喷漆工对有机溶剂混合物的接触。肝脏酶的血清活性。
Scand J Work Environ Health. 1982 Jun;8(2):137-40. doi: 10.5271/sjweh.2491.
6
Benzene as a leukemogenic and carcinogenic agent.
Am J Ind Med. 1985;8(1):9-20. doi: 10.1002/ajim.4700080103.
7
Benzene hematotoxicity and leukemogenesis.
Am J Ind Med. 1985;7(5-6):447-56. doi: 10.1002/ajim.4700070509.
8
The neurotoxicity of industrial solvents: a review of the literature.工业溶剂的神经毒性：文献综述
Am J Ind Med. 1985;8(3):207-17. doi: 10.1002/ajim.4700080306.
9
Effects of long-term exposure to solvents in the paint industry. A cross-sectional epidemiologic study with clinical and laboratory methods.油漆行业长期接触溶剂的影响。一项采用临床和实验室方法的横断面流行病学研究。
Scand J Work Environ Health. 1985;11 Suppl 2:1-28.
10
Increased isotransferrin ratio and reduced erythrocyte and platelet volumes in blood from thermoplastic industry workers.热塑性塑料行业工人血液中异铁传递蛋白比率升高，红细胞和血小板体积减小。
Ann Occup Hyg. 1990 Aug;34(4):391-7. doi: 10.1093/annhyg/34.4.391.

汽车修理喷漆工和汽车修理工的红细胞体积增加。

Increased erythrocyte volume in car repair painters and car mechanics.

作者信息

Beving H, Tornling G, Olsson P

机构信息

Department of Experimental Surgery, Thoracic Clinics, Stockholm, Sweden.

出版信息

Br J Ind Med. 1991 Jul;48(7):499-501. doi: 10.1136/oem.48.7.499.

DOI:10.1136/oem.48.7.499
PMID:1854652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1035404/
Abstract

The biological effect of occupational long term low level exposure to organic solvents was studied in 17 car repair painters and 28 car mechanics, and compared with a control group consisting of 46 healthy men not exposed to organic solvents. The erythrocyte count (RBC) was significantly decreased for both the painters and the mechanics compared with the control group, and a significant increase in the mean erythrocyte volume (MCV) was seen in painters. The mode in size distribution of the erythrocytes (MAXRBC) was shifted towards larger cell volumes for both painters and mechanics. When data from painters and mechanics were combined, the exposed group showed a significantly reduced erythrocyte count (RBC), an increased mean erythrocyte volume (MVC), and an increased mean platelet volume (MPV) compared with the controls. Exposure measurements in combination with analysis of haematological parameters may be a tool for early detection of cellular changes in the blood caused by exposure to solvents, before the appearance of clinical symptoms.

摘要

对17名汽车修理喷漆工和28名汽车修理工进行了研究，以探讨职业性长期低水平接触有机溶剂的生物学效应，并与由46名未接触有机溶剂的健康男性组成的对照组进行比较。与对照组相比，喷漆工和修理工的红细胞计数（RBC）均显著降低，喷漆工的平均红细胞体积（MCV）显著增加。喷漆工和修理工的红细胞大小分布模式（MAXRBC）均向更大的细胞体积偏移。当将喷漆工和修理工的数据合并时，与对照组相比，暴露组的红细胞计数（RBC）显著降低，平均红细胞体积（MVC）增加，平均血小板体积（MPV）增加。将接触测量与血液学参数分析相结合，可能是在临床症状出现之前早期检测因接触溶剂导致血液中细胞变化的一种工具。