Cheung Bernard M Y, Wat Nelson M S, Tso Annette W K, Tam Sidney, Thomas G Neil, Leung Gabriel M, Tse Hung Fat, Woo Jean, Janus Edward D, Lau Chu Pak, Lam Tai Hing, Lam Karen S L
Department of Medicine, University of Hong Kong, Hong Kong, China.
Diabetes Care. 2008 Sep;31(9):1889-91. doi: 10.2337/dc08-0405. Epub 2008 Jun 12.
To investigate the association between raised blood pressure and dysglycemia.
We studied the association between raised blood pressure and dysglycemia in 1,862 subjects in the Hong Kong Cardiovascular Risk Factor Prevalence Study cohort. We determined the factors predicting the development of diabetes and hypertension in 1,496 subjects who did not have either condition at baseline.
Diabetes and hypertension were both related to age, obesity indexes, blood pressure, glucose, HDL cholesterol, and triglycerides. Of subjects with diabetes, 58% had raised blood pressure. Of subjects with hypertension, 56% had dysglycemia. BMI and blood glucose 2 h after a 75-g oral glucose load were independent predictors of new-onset diabetes. Age, systolic blood pressure, and 2-h glucose were independent predictors of new-onset hypertension. BMI, systolic blood pressure, and 2-h glucose were independent predictors of the development of diabetes and hypertension together.
Diabetes and hypertension share common etiological factors. Patients with diabetes or hypertension should be screened and managed for the precursor of the other condition.
研究血压升高与血糖异常之间的关联。
在香港心血管危险因素患病率研究队列中的1862名受试者中，我们研究了血压升高与血糖异常之间的关联。我们确定了在基线时既无糖尿病也无高血压的1496名受试者中预测糖尿病和高血压发生的因素。
糖尿病和高血压均与年龄、肥胖指数、血压、血糖、高密度脂蛋白胆固醇和甘油三酯有关。在糖尿病患者中，58%的人血压升高。在高血压患者中，56%的人存在血糖异常。体重指数（BMI）和75克口服葡萄糖负荷后2小时的血糖是新发糖尿病的独立预测因素。年龄、收缩压和2小时血糖是新发高血压的独立预测因素。BMI、收缩压和2小时血糖是糖尿病和高血压共同发生的独立预测因素。
糖尿病和高血压有共同的病因因素。糖尿病或高血压患者应筛查并管理另一种疾病的前驱因素。
