从明日叶茎中提取的具有超氧化物清除活性的C-香叶基查耳酮。
C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity.
作者信息
Aoki Nobuwa, Muko Mai, Ohta Emi, Ohta Shinji
机构信息
Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan.
出版信息
J Nat Prod. 2008 Jul;71(7):1308-10. doi: 10.1021/np800187f. Epub 2008 Jun 18.
PMID:18558745
Abstract
An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures of 1-3 were determined on the basis of the analysis of their spectroscopic data. Compounds 1-4 exhibited potent superoxide-scavenging activity.
摘要
对明日叶茎甲醇提取物的乙酸乙酯可溶部分进行色谱分离，除了得到一种已知的查耳酮——黄当归醇B（4）之外，还得到了三种新的查耳酮，命名为黄明日叶素A - C（1 - 3）。通过对其光谱数据的分析确定了1 - 3的结构。化合物1 - 4表现出强大的超氧化物清除活性。
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