Chaudhary Monica, Kashyap Bineeta, Gautam Hitender, Saini Sanjeev, Bhalla Preena
Department of Microbiology, Maulana Azad Medical College, New Delhi, India.
Viral Immunol. 2008 Jun;21(2):263-6. doi: 10.1089/vim.2007.0083.
Limited data on acute phase C-reactive protein (CRP) levels in human immunodeficiency virus (HIV) infection exist. The relationship of CRP with HIV was assessed in 119 HIV-positive patients and correlated with CD4 counts and mortality at 1 y. CRP was negatively correlated with CD4 counts with levels of CRP being highest in the group with CD4 counts below 200 cells/microL. It was an indicator of mortality and hence may serve as a useful and inexpensive predictor of HIV disease progression.
关于人类免疫缺陷病毒(HIV)感染时急性期C反应蛋白(CRP)水平的数据有限。对119例HIV阳性患者评估了CRP与HIV的关系,并与1年时的CD4细胞计数和死亡率进行了关联分析。CRP与CD4细胞计数呈负相关,CD4细胞计数低于200个/微升的组中CRP水平最高。它是死亡率的一个指标,因此可能作为HIV疾病进展的一种有用且廉价的预测指标。