Smith Janine, Nichols Kelly K, Baldwin Edward K
National Eye Institute/NIH/DHHS, Bethesda, MD, USA.
Cornea. 2008 Jul;27(6):656-62. doi: 10.1097/QAI.0b013e3181605b95.
To clarify the roles of objective signs and subjective symptoms in the diagnosis and management of dry eye by describing their use by a group of expert practitioners. Dry eye signs and symptoms do not always correlate well, and there is currently some controversy over the ideal roles of signs and symptoms and their actual use in clinical practice.
A balanced panel of 16 participants in a scientific roundtable on dry eye reviewed 4 patient case studies and completed surveys ranking common diagnostic procedures assessing symptoms and signs by the order in which they would be used.
Symptom assessment was the predominant diagnostic method. The objective tests most commonly used during the initial examination were tear breakup time (93%), corneal staining (85%), tear film assessment (76%), conjunctival staining (74%), and the Schirmer test (54%). Most panelists used multiple tests, with a median of 6 tests used in the initial examination.
Subjective symptoms and objective signs are both important in the diagnosis and management of dry eye, with the patient's symptoms and history playing a critical role. Most clinicians use objective signs in dry eye management. However, currently available diagnostic tests do not correlate reliably with symptom severity. Research aimed at developing accurate, objective, responsive measures of dry eye severity is needed.
通过描述一组专家从业者对客观体征和主观症状的使用情况,来阐明它们在干眼诊断和管理中的作用。干眼的体征和症状并不总是密切相关,目前对于体征和症状的理想作用及其在临床实践中的实际应用存在一些争议。
干眼科学圆桌会议的16名参与者组成了一个均衡的小组,他们回顾了4个患者案例研究,并完成了调查,按照使用顺序对评估症状和体征的常见诊断程序进行排序。
症状评估是主要的诊断方法。初次检查时最常用的客观检查是泪膜破裂时间(93%)、角膜染色(85%)、泪膜评估(76%)、结膜染色(74%)和泪液分泌试验(54%)。大多数小组成员使用多种检查,初次检查中使用检查的中位数为6项。
主观症状和客观体征在干眼的诊断和管理中都很重要,患者的症状和病史起着关键作用。大多数临床医生在干眼管理中使用客观体征。然而,目前可用的诊断检查与症状严重程度的相关性并不可靠。需要开展旨在开发准确、客观、反映干眼严重程度的测量方法的研究。