Tatara Marcin R, Sliwa Ewa, Dudek Katarzyna, Gawron Antoni, Piersiak Tomasz, Dobrowolski Piotr, Mosiewicz Jerzy, Siwicki Andrzej, Studzinski Tadeusz
Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 12, 20-950 Lublin, Poland.
Ann Agric Environ Med. 2008;15(1):63-9.
This study was performed to investigate whether postnatal administration with aged garlic extract (AGE) and allicin influences performance and systemic development of piglets exposed to early weaning. Twenty-four male piglets were weaned from sows at the age of two days of life, divided into 4 weight-matched groups and kept under conditions of artificial sow for 6 days. The first group consisted of control animals, while piglets that were given AGE daily per os at the dosages of 1 ml and 2 ml/kg body weight, respectively belonged to the second and third group. The fourth group consisted of piglets administered orally with allicin at the dosage of 1.0 mg/kg body weight/day. At the age of 8 days of life all animals were sacrificed. Next to body weight gain and morphological properties of the gastrointestinal tract, the haematological examination was performed, and activity of lysozyme and ceruloplasmin as well as level of gamma-globulins were determined. The obtained results showed that AGE and allicin improved final body weight, morphological properties of intestine villi and non-specific defence mechanisms of pigs. All these results indicate that AGE and allicin induced beneficial effects on health status, performance and systemic development of piglets.
本研究旨在调查产后给予 aged garlic extract（AGE， aged garlic extract，直译为“老化大蒜提取物”，可理解为“陈蒜提取物”之类的意思）和大蒜素是否会影响早期断奶仔猪的生长性能和全身发育。24 头雄性仔猪在出生 2 日龄时从母猪处断奶，分为 4 个体重匹配组，并在人工母猪条件下饲养 6 天。第一组为对照动物，第二组和第三组仔猪分别按 1 ml/kg 和 2 ml/kg 体重的剂量每日经口给予 AGE。第四组仔猪按 1.0 mg/kg 体重/天的剂量经口给予大蒜素。在 8 日龄时处死所有动物。除了测定体重增加和胃肠道的形态学特性外，还进行了血液学检查，并测定了溶菌酶和铜蓝蛋白的活性以及γ-球蛋白水平。所得结果表明，AGE 和大蒜素改善了猪的终末体重、肠绒毛的形态学特性和非特异性防御机制。所有这些结果表明，AGE 和大蒜素对仔猪的健康状况、生长性能和全身发育具有有益影响。
