Di Silverio Franco, Sciarra Alessandro, Parente Ulderico, Andrea Alfarone, Von Heland Magnus, Panebianco Valeria, Passariello Roberto
Department of Urology, University of Rome, Rome, Italy.
Urol Int. 2008;80(4):451-3. doi: 10.1159/000132708. Epub 2008 Jun 27.
A 71-year-old man with advanced left renal cell carcinoma (lymph node involvement and vena cava thrombus) was submitted to 6 months of neoadjuvant treatment with sorafenib before open radical nephrectomy. After sorafenib treatment and before surgery a new CT scan confirmed the presence of a 9.0 cm in diameter solid mass in the left kidney but a reduction in thrombus extension, limited to the left renal vein. At histological examination after radical nephrectomy, over 90% of the renal mass was substituted by necrotic tissue.
一名71岁的男性患有晚期左肾细胞癌（伴有淋巴结转移和腔静脉血栓形成），在接受开放性根治性肾切除术之前接受了6个月的索拉非尼新辅助治疗。在索拉非尼治疗后且手术前，一次新的CT扫描证实左肾存在一个直径9.0厘米的实性肿块，但血栓延伸范围缩小，仅限于左肾静脉。根治性肾切除术后的组织学检查显示，超过90%的肾脏肿块被坏死组织替代。
