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[河边艾中黄酮类化合物的研究]

[Studies on flavonoids from Blumea riparia].

作者信息

Cao Jia-Qing, Sun Shu-Wei, Chen Huan, Wang Ya-Nan, Pei Yue-Hu

机构信息

School of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(7):782-4.

PMID:18589780
Abstract

OBJECTIVE

To separate and identify the chemical constituents of Blumea riparia.

METHOD

The compounds were separated and purified by repeated silica gel, Sephadex LH -20 column chromatographiy. The structures of these compounds isolated were identified by analysis of their spectral data, physical and chemical properties.

RESULT

Six flavonoids were isolated from B. riparia. and their structures were identified as eriodictyol-7, 4'-dimethyl ether (1), eriodictyol-7, 3'-dimethyl ether (2), eriodictyol-7-methyl ether (3), quercetin-7, 3', 4'-trimethyl ether (4), tamarixetin (5), rhamnocitrin (6).

CONCLUSION

Compound 1-6 were obtained from B. riparia for the first time.

摘要

目的

分离并鉴定河边艾的化学成分。

方法

通过反复硅胶柱色谱、葡聚糖凝胶LH -20柱色谱对化合物进行分离纯化。通过对分离得到的化合物的光谱数据、理化性质分析鉴定其结构。

结果

从河边艾中分离得到6个黄酮类化合物,其结构分别鉴定为圣草酚-7,4'-二甲醚(1)、圣草酚-7,3'-二甲醚(2)、圣草酚-7-甲醚(3)、槲皮素-7,3',4'-三甲醚(4)、柽柳素(5)、鼠李柠檬素(6)。

结论

化合物1 - 6首次从河边艾中获得。

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