Kuwabara K, Imanaka Y, Matsuda S, Fushimi K, Hashimoto H, Ishikawa K B, Horiguchi H, Hayashida K, Fujimor K
Kyushu University, Graduate School of Medical Sciences, Department of Health Care Administration and Management, Kyushu University.
Clin Ter. 2008 May-Jun;159(3):155-63.
There are several literatures on outcome variations between patients treated with an open appendectomy (OA) and a laparoscopic appendectomy (LA). However, there are no studies assessing differences in cost and outcome that adjust for age and hospital function or region. This study examines the differences in cost and procedure-related complications of OA and LA procedures.
This study contains 1703 appendectomy patients treated for appendicitis in 76 academic hospitals and 80 community hospitals. Demographic variables, clinical variables, length of stay (LOS), total charges (TC; US$) and complication rates were analyzed for both OA and LA procedures. The specific contributions of LA to LOS, TC, and complication rate were identified using multivariate analysis.
1469 (86.3%) patients underwent OA and 234 (13.7%) underwent LA. Complicated appendicitis was diagnosed in 13.1% of OA cases and 15.4% of LA cases. The complication rates were 3.4% in OA and 2.6% in LA (p=0.504). There were significant differences in LOS and TC by severity of appendicitis and by procedure type. After risk adjustment for the other study variables, LA was associated with a higher TC than OA ($1458, p0.001). However there were no significant differences in LOS or complication rates between the two treatment groups.
This study suggests that LA increases cost, but has no significant impact on LOS or complication rates. However, other outcomes such as quality of life or subgroup analysis for obese patients are needed for a more complete economic analysis of OA and LA.
有几篇关于开腹阑尾切除术(OA)和腹腔镜阑尾切除术(LA)治疗患者结局差异的文献。然而,尚无研究评估在调整年龄、医院功能或地区因素后成本和结局的差异。本研究探讨OA和LA手术在成本及手术相关并发症方面的差异。
本研究纳入了76家学术医院和80家社区医院中因阑尾炎接受阑尾切除术的1703例患者。分析了OA和LA手术的人口统计学变量、临床变量、住院时间(LOS)、总费用(TC;美元)及并发症发生率。采用多变量分析确定LA对LOS、TC和并发症发生率的具体影响。
1469例(86.3%)患者接受了OA手术,234例(13.7%)接受了LA手术。OA病例中13.1%诊断为复杂性阑尾炎,LA病例中15.4%为复杂性阑尾炎。OA的并发症发生率为3.4%,LA为2.6%(p = 0.504)。阑尾炎严重程度和手术类型不同,LOS和TC存在显著差异。在对其他研究变量进行风险调整后,LA的TC高于OA(1458美元,p<0.001)。然而,两个治疗组在LOS或并发症发生率方面无显著差异。
本研究表明,LA增加了成本,但对LOS或并发症发生率无显著影响。然而,为了对OA和LA进行更全面的经济分析,还需要其他结局指标,如生活质量或肥胖患者的亚组分析。