Sporn Emanuel, Petroski Gregory F, Mancini Gregory J, Astudillo J Andres, Miedema Brent W, Thaler Klaus
Department of Surgery, School of Medicine, University of Missouri-Columbia, Columbia, MO, USA.
J Am Coll Surg. 2009 Feb;208(2):179-85.e2. doi: 10.1016/j.jamcollsurg.2008.10.026.
Although laparoscopic appendectomy is widely used for treatment of appendicitis, it is still unclear if it is superior to the open approach.
From the Nationwide Inpatient Sample 2000 to 2005, hospitalizations with the primary ICD-9 procedure code of laparoscopic (LA) and open appendectomy (OA) were included in this study. Outcomes of length of stay, costs, and complications were assessed by stratified analysis for uncomplicated and complicated appendicitis (perforation or abscess). Regression methods were used to adjust for covariates and to detect trends. Costs were rescaled using the hospital and related services portion of the Medical Consumer Price Index.
Between 2000 and 2005, 132,663 (56.3%) patients underwent OA and 102,810 (43.7%) had LA. Frequency of LA increased from 32.2% to 58.0% (p < 0.001); conversion rates decreased from 9.9% to 6.9% (p < 0.001). Covariate adjusted length of stay for LA was approximately 15% shorter than for OA in both uncomplicated and complicated cases (p < 0.001). Adjusted costs for LA were 22% higher in uncomplicated appendicitis and 9% higher in patients with complicated appendicitis (p < 0.001). Costs and length of stay decreased over time in OA and LA. The risk for a complication was higher in the LA group (p < 0.05, odds ratio=1.07, 95% CI 1.00 to 1.14) with uncomplicated appendicitis.
LA results in higher costs and increased morbidity for patients with uncomplicated appendicitis. Nevertheless, LA is increasingly used. Patients undergoing LA benefit from a slightly shorter hospital stay. In general, open appendectomy may be the preferred approach for patients with acute appendicitis, with indication for LA in selected subgroups of patients.
尽管腹腔镜阑尾切除术被广泛用于治疗阑尾炎,但它是否优于开放手术仍不明确。
从2000年至2005年的全国住院患者样本中,本研究纳入了主要ICD - 9手术编码为腹腔镜阑尾切除术(LA)和开放阑尾切除术(OA)的住院病例。通过对单纯性和复杂性阑尾炎(穿孔或脓肿)进行分层分析,评估住院时间、费用和并发症等结果。采用回归方法对协变量进行调整并检测趋势。费用使用医疗消费者价格指数中的医院及相关服务部分进行重新调整。
在2000年至2005年期间,132,663例(56.3%)患者接受了OA,102,810例(43.7%)接受了LA。LA的使用频率从32.2%增至58.0%(p < 0.001);中转率从9.9%降至6.9%(p < 0.001)。在单纯性和复杂性病例中,经协变量调整后的LA住院时间比OA短约15%(p < 0.001)。在单纯性阑尾炎中,LA的调整后费用高22%,在复杂性阑尾炎患者中高9%(p < 0.001)。OA和LA的费用及住院时间随时间推移而减少。在单纯性阑尾炎患者中,LA组的并发症风险更高(p < 0.05,优势比 = 1.07,95%可信区间1.00至1.14)。
对于单纯性阑尾炎患者,LA导致更高的费用和发病率增加。尽管如此,LA的使用仍日益增多。接受LA的患者受益于稍短的住院时间。总体而言,开放阑尾切除术可能是急性阑尾炎患者的首选方法,对于特定亚组患者可考虑LA。