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应对复杂问题。对联会复合体的多学科研究方法。

Coming to grips with a complex matter. A multidisciplinary approach to the synaptonemal complex.

作者信息

Loidl J

机构信息

Department of Cytology and Genetics, University of Vienna, Austria.

出版信息

Chromosoma. 1991 Jun;100(5):289-92. doi: 10.1007/BF00360526.

DOI:10.1007/BF00360526
PMID:1860374
Abstract

Research into the synaptonemal complex (SC) is currently finding renewed interest. This is because the primarily cytological knowledge of the SC has been increasingly supplemented by immunochemical characterization and genetical studies over recent years. Moreover, yeast, offering one of the most handy and rewarding experimental systems, has joined the group of organisms in which the SC can be studied cytologically. In this essay I shall present aspects concerning the SC and its role in meiotic pairing that have emerged over the past few years, parts of which were discussed at a recent meeting in Obertraun, Austria.

摘要

目前,对联会复合体(SC)的研究再度引起了人们的兴趣。这是因为近年来,关于SC的主要细胞学知识越来越多地得到了免疫化学特征分析和遗传学研究的补充。此外,酵母作为最便捷且有价值的实验系统之一,已加入到能够对SC进行细胞学研究的生物群体中。在本文中,我将阐述过去几年中出现的有关SC及其在减数分裂配对中作用的一些方面,其中部分内容曾在最近于奥地利上特劳恩召开的一次会议上进行过讨论。

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本文引用的文献

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A structural analysis of the role of the nuclear matrix and DNA loops in the organization of the nucleus and chromosome.核基质和DNA环在细胞核及染色体组织中的作用的结构分析
J Cell Sci Suppl. 1984;1:123-35. doi: 10.1242/jcs.1984.supplement_1.9.
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The synaptonemal complex in genetic segregation.遗传分离中的联会复合体。
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The fine structure of euchromatin and centromeric heterochromatin in Tenebrio molitor chromosomes.黄粉虫染色体中常染色质和着丝粒异染色质的精细结构。
以高粱基因组为基础,推动禾本科植物和谷物的比较遗传图谱、物理图谱、多样性图谱及细胞分子图谱的整合。
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Unusual nuclear structures in meiotic prophase of fission yeast: a cytological analysis.裂殖酵母减数分裂前期的异常核结构:细胞学分析
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The role of the ameiotic1 gene in the initiation of meiosis and in subsequent meiotic events in maize.无减数分裂1基因在玉米减数分裂起始及后续减数分裂事件中的作用。
Genetics. 1993 Dec;135(4):1151-66. doi: 10.1093/genetics/135.4.1151.
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Homologous pairing is reduced but not abolished in asynaptic mutants of yeast.在酵母的非联会突变体中,同源配对减少但并未消除。
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Cytological aspects of meiotic recombination.减数分裂重组的细胞学方面
Experientia. 1994 Mar 15;50(3):285-94. doi: 10.1007/BF01924012.
9
The relationship between synaptonemal complex length and genome size in four vertebrate classes (Osteicthyes, Reptilia, Aves, Mammalia).四种脊椎动物类别(硬骨鱼纲、爬行纲、鸟纲、哺乳纲)中联会复合体长度与基因组大小之间的关系。
Chromosome Res. 1994 Mar;2(2):153-62. doi: 10.1007/BF01553494.
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Analysis of cDNA sequences from mouse testis.小鼠睾丸cDNA序列分析。
Mamm Genome. 1994 Sep;5(9):557-65. doi: 10.1007/BF00354930.
Chromosoma. 1985;91(3-4):287-96. doi: 10.1007/BF00328224.
4
Gene conversion, recombination nodules, and the initiation of meiotic synapsis.基因转换、重组节与减数分裂联会的起始
Bioessays. 1987 May;6(5):232-6. doi: 10.1002/bies.950060510.
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The metaphase scaffold is helically folded: sister chromatids have predominantly opposite helical handedness.
Cell. 1988 Dec 23;55(6):937-44. doi: 10.1016/0092-8674(88)90239-5.
6
Genetic control of chromosome synapsis in yeast meiosis.酵母减数分裂中染色体联会的遗传控制。
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7
Synaptonemal complex proteins.联会复合体蛋白
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HOP1: a yeast meiotic pairing gene.HOP1:一种酵母减数分裂配对基因。
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9
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