Franceschi S, Serraino D, La Vecchia C, Bidoli E, Tirelli U
Epidemiology Unit, Aviano Cancer Center, Italy.
Int J Cancer. 1991 Jul 30;48(6):831-5. doi: 10.1002/ijc.2910480608.
The relationship between occupation and exposure to several occupational agents and Hodgkin's disease (HD) was investigated in a case-control study of 152 cases and 613 controls with acute diseases admitted to all hospitals in Pordenone province, north-east Italy. Among cases, there was a significant excess of individuals occupied in agriculture (odds ratio, OR for greater than 10 years = 2.2, 95% confidence interval, CI:1.3-3.7), who were exposed to livestock and meat processing (OR = 3.4, 95% CI:1.7-6.6), herbicides and pesticides (OR = 3.2, 95% CI:1.6-6.5). When the relationship between agriculture and specific exposures was assessed, it appeared that contact with some still unidentified animal-related agent involved in livestock farming and meat processing may be at least as important in determining HD risk as exposure to herbicides and pesticides and, probably, more important than occupation in agriculture per se.
在一项病例对照研究中，对意大利东北部波代诺内省所有医院收治的152例霍奇金淋巴瘤（HD）患者和613例急性病对照者进行了职业与几种职业接触因素和HD之间关系的调查。在病例组中，从事农业工作的个体显著过多（从事农业超过10年的比值比，OR = 2.2，95%置信区间，CI：1.3 - 3.7），这些个体接触牲畜和肉类加工（OR = 3.4，95% CI：1.7 - 6.6）、除草剂和杀虫剂（OR = 3.2，95% CI：1.6 - 6.5）。当评估农业与特定接触之间的关系时，发现接触畜牧养殖和肉类加工中一些仍未明确的与动物相关的因素，在确定HD风险方面可能至少与接触除草剂和杀虫剂一样重要，而且可能比单纯从事农业工作更重要。
