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小儿特应性皮炎:食物过敏原的重要性

Pediatric atopic dermatitis: the importance of food allergens.

作者信息

Kim Jennifer S

机构信息

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Semin Cutan Med Surg. 2008 Jun;27(2):156-60. doi: 10.1016/j.sder.2008.05.003.

Abstract

Food allergy and atopic dermatitis often occur in the same patients. Food-induced eczema may be perceived as a controversial topic because the immunologic mechanisms have yet to be fully elucidated. Nevertheless, published clinical studies have clearly demonstrated that foods can induce symptoms in a subset of patients with atopic dermatitis. Those at greatest risk are young children in whom eczematous lesions are severe or recalcitrant to therapy. Allergy testing can be helpful but must be applied judiciously. A medical history obtained by a skilled and knowledgeable health care provider is of paramount importance to interpret test results appropriately. Finally, the implementation of proper dietary avoidance can improve symptoms and provide safety from potentially fatal anaphylaxis. However, if inappropriate prescribed, elimination diets can have significant negative nutritional and social consequences.

摘要

食物过敏和特应性皮炎常发生于同一患者。食物诱发的湿疹可能被视为一个有争议的话题,因为其免疫机制尚未完全阐明。然而,已发表的临床研究清楚地表明,食物可在一部分特应性皮炎患者中诱发症状。风险最高的是患有严重湿疹性皮损或治疗效果不佳的幼儿。过敏检测可能会有帮助,但必须谨慎应用。由经验丰富且知识渊博的医疗服务提供者获取的病史对于正确解读检测结果至关重要。最后,实施适当的饮食回避可改善症状并预防潜在的致命性过敏反应。然而,如果处方不当,排除饮食可能会产生重大的负面营养和社会后果。

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