Smolders G J, van der Meij J, van Loosdrecht M C, Heijnen J J
Department of Biochemical Engineering, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands.
Biotechnol Bioeng. 1995 Aug 5;47(3):277-87. doi: 10.1002/bit.260470302.
A structured metabolic model is developed that describes the stoichiometry and kinetics of the biological P removal process. In this approach all relevant metabolic reactions underlying the metabolism, considering also components like adenosine triphosphate (ATP) and nic-otinamide-adenine dinucleotide (NADH(2)) are describedbased on biochemical pathways. As a consequence of the relations between the stoichiometry of the metabolic reactions and the reaction rates of components, the required number of kinetic relations to describe the process is reduced. The model describes the dynamics of the storage compounds which are considered separately from the active biomass. The model was validated in experiments at a constant sludge retention time of 8 days, over the anaerobic and aerobic phases in which the external oncentrations as well as the internal fractions of the relevant components involved in the P-removal process were monitored. These measurements include dissolved acetate, phosphate, and ammonium; oxygen consumption; poly-beta-hydroxybutyrate (PHB); glycogen; and active biomass. The model satisfactorily describes the dynamic behavior of all components during the anaerobicand aerobic phases.(c) 1995 John Wiley & Sons, Inc.
开发了一种结构化代谢模型，该模型描述了生物除磷过程的化学计量和动力学。在这种方法中，基于生化途径描述了代谢过程中所有相关的代谢反应，同时还考虑了三磷酸腺苷（ATP）和烟酰胺腺嘌呤二核苷酸（NADH(2)）等成分。由于代谢反应的化学计量与各成分反应速率之间的关系，减少了描述该过程所需的动力学关系数量。该模型描述了与活性生物质分开考虑的储存化合物的动态变化。该模型在污泥停留时间恒定为8天的实验中得到验证，实验涵盖厌氧和好氧阶段，在此期间监测了除磷过程中相关成分的外部浓度以及内部组分。这些测量包括溶解的乙酸盐、磷酸盐和铵；氧气消耗；聚-β-羟基丁酸酯（PHB）；糖原；以及活性生物质。该模型令人满意地描述了厌氧和好氧阶段所有成分的动态行为。(c) 1995约翰·威利父子公司。
