圆锥角膜中的角膜滞后和角膜阻力因子：使用Reichert眼反应分析仪的研究结果
Corneal hysteresis and corneal resistance factor in keratoectasia: findings using the Reichert ocular response analyzer.
作者信息
Kirwan Caitriona, O'Malley Donal, O'Keefe Michael
机构信息
Mater Private Hospital, University College Dublin, Dublin, Ireland.
出版信息
Ophthalmologica. 2008;222(5):334-7. doi: 10.1159/000145333. Epub 2008 Jul 15.
AIM
To examine corneal hysteresis (CH) and corneal resistance factor (CRF) in normal and ectatic corneas.
METHODS
CH and CRF were measured using the Reichert Ocular Response Analyzer in patients with clinically diagnosed keratoconus (KC), forme fruste KC (FFKC) and normal eyes.
RESULTS
21 eyes (13 patients) with clinically diagnosed KC and 30 eyes (18 patients) with FFKC were included in the study. Mean CH and CRF in FFKC did not differ from that in pachymetry-matched normal eyes. KC eyes had significantly lower CH and CRF than normal and FFKC eyes.
CONCLUSION
A significant overlap in CH and CRF values among the 3 groups was evident. Our findings do not indicate a role for CH and CRF measurement as a single test to aid in the detection of early ectasia. It may be of use when used in conjunction with other parameters such as aberrometry. CH and CRF values may prove to be useful in monitoring ectasia progression.
目的
检测正常角膜和扩张性角膜的角膜滞后（CH）和角膜阻力因子（CRF）。
方法
使用Reichert眼反应分析仪对临床诊断为圆锥角膜（KC）、顿挫型圆锥角膜（FFKC）和正常眼的患者测量CH和CRF。
结果
本研究纳入了21只临床诊断为KC的眼睛（13例患者）和30只FFKC的眼睛（18例患者）。FFKC的平均CH和CRF与厚度匹配的正常眼无差异。KC眼的CH和CRF显著低于正常眼和FFKC眼。
结论
三组之间CH和CRF值存在明显重叠。我们的研究结果表明，CH和CRF测量作为一种单独的检测方法，无助于早期扩张性病变的检测。当与其他参数（如像差测量）结合使用时可能有用。CH和CRF值可能有助于监测扩张性病变的进展。
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