构建秀丽隐杆线虫的细胞与解剖本体论。
Building a cell and anatomy ontology of Caenorhabditis elegans.
作者信息
Lee Raymond Y N, Sternberg Paul W
机构信息
WormBase, California Institute of Technology, Pasadena, CA 91125, USA.
出版信息
Comp Funct Genomics. 2003;4(1):121-6. doi: 10.1002/cfg.248.
Abstract
We are endowed with a rich knowledge about Caenorhabditis elegans. Its stereotyped anatomy and development has stimulated research and resulted in the accumulation of cell-based information concerning gene expression, and the role of specific cells in developmental signalling and behavioural circuits. To make the information more accessible to sophisticated queries and automated retrieval systems, WormBase has begun to construct a C. elegans cell and anatomy ontology. Here we present our strategies and progress.
摘要
我们对秀丽隐杆线虫拥有丰富的知识。其固定的解剖结构和发育过程激发了研究，并积累了有关基因表达的基于细胞的信息，以及特定细胞在发育信号传导和行为回路中的作用。为了使这些信息更便于复杂查询和自动检索系统使用，WormBase已开始构建秀丽隐杆线虫细胞与解剖本体。在此，我们展示我们的策略和进展。
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