Witney Adam A, Hinds Jason
Bacterial Microarray Group, Department of Medical Microbiology, St George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK.
Comp Funct Genomics. 2002;3(4):369-71. doi: 10.1002/cfg.197.
The manufacture and use of a whole-genome microarray is a complex process and it is essential that all data surrounding the process is stored, is accessible and can be easily associated with the data generated following hybridization and scanning. As part of a program funded by the Wellcome Trust, the Bacterial Microarray Group at St. George's Hospital Medical School (BmuG@S) will generate whole-genome microarrays for 12 bacterial pathogens for use in collaboration with specialist research groups. BmuG@S will collaborate with these groups at all levels, including the experimental design, methodology and analysis. In addition, we will provide informatic support in the form of a database system (BmuG@Sbase). BmuG@Sbase will provide access through a web interface to the microarray design data and will allow individual users to store their data in a searchable, secure manner. Tools developed by BmuG@S in collaboration with specific research groups investigating analysis methodology will also be made available to those groups using the arrays and submitting data to BmuG@Sbase.
全基因组微阵列的制造和使用是一个复杂的过程，围绕该过程的所有数据都必须进行存储、可访问，并且能够轻松地与杂交和扫描后生成的数据相关联。作为由惠康信托基金会资助的一个项目的一部分，圣乔治医院医学院的细菌微阵列小组（BmuG@S）将为12种细菌病原体生成全基因组微阵列，以供与专业研究小组合作使用。BmuG@S将在各个层面与这些小组合作，包括实验设计、方法学和分析。此外，我们将以数据库系统（BmuG@Sbase）的形式提供信息支持。BmuG@Sbase将通过网络界面提供对微阵列设计数据的访问，并允许个人用户以可搜索、安全的方式存储他们的数据。BmuG@S与研究分析方法的特定研究小组合作开发的工具也将提供给那些使用阵列并将数据提交到BmuG@Sbase的小组。
