Kaufmann Claude, Bachmann Lucas M, Thiel Michael A
Department of Ophthalmology, University of Zurich, Switzerland.
Invest Ophthalmol Vis Sci. 2004 Sep;45(9):3118-21. doi: 10.1167/iovs.04-0018.
The dynamic contour tonometer (DCT; Pascal tonometer) is a novel tonometer designed to measure intraocular pressure (IOP) independent of corneal properties. The purpose of this study was a comparison of the DCT with the Goldmann applanation tonometer (GAT) with respect to mean of IOP readings, the influence of ocular structural factors on IOP readings, and both intra- and interobserver variability, in a large group of healthy subjects.
In a prospective study of 228 eyes, IOP measurements by GAT and DCT were compared, and the effects of central corneal thickness (CCT), corneal curvature, axial length, and anterior chamber depth were analyzed. To evaluate intra- and interobserver variability, IOP was measured in eight eyes by four observers.
There was a high concordance between the IOP readings obtained by DCT and GAT. However, IOP readings were consistently higher with DCT than with GAT (median difference: +1.7 mm Hg, interquartile range [25th-75th percentile] = 0.8-2.7 mm Hg). In contrast to GAT, multivariable regression analysis showed no significant effect of corneal thickness, corneal curvature, astigmatism, anterior chamber depth, and axial length on DCT readings. For repeated measurements the intraobserver variability was 0.65 mm Hg for the DCT and 1.1 mm Hg for the GAT (P = 0.008). Interobserver variability was 0.44 mm Hg for the DCT and 1.28 mm Hg for the GAT (P = 0.017).
IOP measurements by DCT are highly concordant with IOP readings obtained from GAT but do not vary in CCT and have a lower intra- and interobserver variability. DCT seems to be an appropriate method of tonometry for routine clinical use.
动态轮廓眼压计(DCT;帕斯卡眼压计)是一种新型眼压计,旨在独立于角膜特性测量眼压(IOP)。本研究的目的是在一大组健康受试者中,比较DCT与Goldmann压平眼压计(GAT)在眼压读数平均值、眼部结构因素对眼压读数的影响以及观察者内和观察者间变异性方面的差异。
在一项对228只眼睛的前瞻性研究中,比较了GAT和DCT测量的眼压,并分析了中央角膜厚度(CCT)、角膜曲率、眼轴长度和前房深度的影响。为了评估观察者内和观察者间的变异性,四名观察者对八只眼睛进行了眼压测量。
DCT和GAT获得的眼压读数之间具有高度一致性。然而,DCT测得的眼压读数始终高于GAT(中位数差异:+1.7 mmHg,四分位间距[第25 - 75百分位数]=0.8 - 2.7 mmHg)。与GAT不同,多变量回归分析显示角膜厚度、角膜曲率、散光、前房深度和眼轴长度对DCT读数无显著影响。对于重复测量,DCT的观察者内变异性为0.65 mmHg,GAT为1.1 mmHg(P = 0.008)。DCT的观察者间变异性为0.44 mmHg,GAT为1.28 mmHg(P = 0.017)。
DCT测量的眼压与GAT获得的眼压读数高度一致,但不受CCT影响,且观察者内和观察者间变异性较低。DCT似乎是一种适用于常规临床使用的眼压测量方法。