Andreanos Konstantinos, Koutsandrea Chryssanthi, Papaconstantinou Dimitris, Diagourtas Andreas, Kotoulas Andreas, Dimitrakas Panagiotis, Moschos Marilita M
First Department of Ophthalmology, University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece.
Clin Ophthalmol. 2016 Dec 9;10:2477-2484. doi: 10.2147/OPTH.S115203. eCollection 2016.
The aim of the study was to assess the influence of central corneal thickness (CCT) and corneal curvature in tonometry measurements taken by Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (DCT).
This was a prospective study of 185 eyes from 97 subjects, attending outpatient ophthalmology appointments, who underwent intraocular pressure measurements by GAT and Pascal DCT. CCT and corneal curvature were obtained using ultrasound pachymetry and Orbscan topography, respectively. All measurements were carried out among males and females during the period 2009-2012. Apart from the usual descriptive and exploratory data analysis, one-way analysis of variance and agreement analysis were performed, linear as well as intraclass correlation coefficients were estimated, and multiple scatter and Bland-Altman plots were produced.
Mean IOP measurements obtained were 17.21±4.10 mmHg by DCT and 13.23±4.07 mmHg by GAT. Mean difference between the GAT and DCT measurements was 3.88±2.8 mmHg. Mean CCT and corneal curvature were 522.78±52 μm and 43.83±2.9823 D, respectively.
Intraocular pressure measured by GAT was consistently lower when compared with DCT, and this difference was greatest with thinner CCT. Flat corneas seem to influence GAT measurements compared to DCT.
本研究旨在评估中央角膜厚度(CCT)和角膜曲率对Goldmann压平眼压计(GAT)和帕斯卡动态轮廓眼压计(DCT)所测眼压的影响。
这是一项对97名受试者的185只眼睛进行的前瞻性研究,这些受试者前来眼科门诊就诊,接受了GAT和帕斯卡DCT眼压测量。分别使用超声测厚法和Orbscan地形图仪获取CCT和角膜曲率。所有测量均在2009年至2012年期间对男性和女性进行。除了常规的描述性和探索性数据分析外,还进行了单因素方差分析和一致性分析,估计了线性以及组内相关系数,并绘制了多重散点图和布兰德-奥特曼图。
DCT测得的平均眼压为17.21±4.10 mmHg,GAT测得的平均眼压为13.23±4.07 mmHg。GAT和DCT测量值之间的平均差异为3.88±2.8 mmHg。平均CCT和角膜曲率分别为522.78±52μm和43.83±2.9823 D。
与DCT相比,GAT测量的眼压始终较低,且这种差异在CCT较薄时最大。与DCT相比,扁平角膜似乎会影响GAT测量值。