Tazi Illias, Hidane Zakia, Zafad Saadia, Harif Mhamed, Benchekroun Said, Ribeiro Raul
Hematology and Pediatric Oncology Department, Hopital, 20 Aout 1953, Casablanca, Morocco.
Pediatr Blood Cancer. 2008 Oct;51(4):495-8. doi: 10.1002/pbc.21689.
Nutritional assessment is an essential component of the initial assessment of children with cancer. Malnutrition may be present at diagnosis due to the effects of the malignancy or, in low income countries (LIC), due to poverty and an inadequate diet.
The aim of this study is to evaluate the prevalence of malnutrition at diagnosis in children with cancer in Morocco.
Nutritional status of 100 children aged less than 18 years with newly diagnosed malignancy between January 2005 and January 2006 was evaluated by anthropometric and biochemical parameters before initiating therapy. We measured weight, height, weight-for-height using z-scores index for children and body mass index for adolescents, triceps skinfold thickness and mid-upper arm circumference, and serum albumin.
A total of 100 patients were included. The mean age was 7 years (range 1 to 18 years). Sixty percent were boys. The diagnosis was: Burkitt lymphoma (n = 19), acute myeloblastic leukaemia (n = 18), acute lymphoblastic leukaemia (n = 14), rhabdomyosarcoma (n = 13), Ewing sarcoma (n = 7), nephroblastoma (n = 6), Hodgkin disease (n = 5), osteosarcoma (n = 5), retinoblastoma (n = 4), neuroblastoma (n = 3), germ cell tumor (n = 3), orbital lymphoma (n = 1), cerebral lymphoma (n = 1), ependymoma (n = 1). Incidence of malnutrition ranged from 20 to 50%, depending upon the measurement used.
The prevalence of malnutrition in this study was high, so interventions are being implemented to improve the nutritional status of these patients.
营养评估是癌症患儿初始评估的重要组成部分。在诊断时,营养不良可能因恶性肿瘤的影响而出现,或者在低收入国家,由于贫困和饮食不足导致。
本研究的目的是评估摩洛哥癌症患儿诊断时营养不良的患病率。
在2005年1月至2006年1月期间,对100名年龄小于18岁的新诊断恶性肿瘤患儿在开始治疗前通过人体测量和生化参数评估营养状况。我们测量了体重、身高、儿童用z评分指数计算的身高别体重以及青少年的体重指数、三头肌皮褶厚度和上臂中部周长,以及血清白蛋白。
共纳入100例患者。平均年龄为7岁(范围1至18岁)。60%为男孩。诊断结果为:伯基特淋巴瘤(n = 19)、急性髓细胞白血病(n = 18)、急性淋巴细胞白血病(n = 14)、横纹肌肉瘤(n = 13)、尤因肉瘤(n = 7)、肾母细胞瘤(n = 6)、霍奇金病(n = 5)、骨肉瘤(n = 5)、视网膜母细胞瘤(n = 4)、神经母细胞瘤(n = 3)、生殖细胞瘤(n = 3)、眼眶淋巴瘤(n = 1)、脑淋巴瘤(n = 1)、室管膜瘤(n = 1)。营养不良的发生率在20%至50%之间,取决于所使用的测量方法。
本研究中营养不良的患病率很高,因此正在实施干预措施以改善这些患者的营养状况。