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每天服用一克阿司匹林并不能降低因胆结石疾病住院的风险。

One gram of aspirin per day does not reduce risk of hospitalization for gallstone disease.

作者信息

Kurata J H, Marks J, Abbey D

机构信息

Department of Family Medicine, San Bernardino County Medical Center, California.

出版信息

Dig Dis Sci. 1991 Aug;36(8):1110-5. doi: 10.1007/BF01297455.

DOI:10.1007/BF01297455
PMID:1864205
Abstract

Data from 4524 patients in a randomized, controlled trial of aspirin were analyzed to determine if aspirin reduced the risk for hospitalization for gallstone disease. Aspirin at a dose of 1000 mg/day did not reduce the risk of hospitalization for gallstones. Hospitalization rates for gallstone disease were consistent with national rates, and the data confirmed previous associations of gallstone disease with age, elevated serum triglycerides, obesity, and female gender.

摘要

对4524例患者参与的阿司匹林随机对照试验数据进行分析，以确定阿司匹林是否能降低胆结石疾病住院风险。每日服用1000毫克剂量的阿司匹林并不能降低胆结石住院风险。胆结石疾病的住院率与全国水平一致，且数据证实了胆结石疾病与年龄、血清甘油三酯升高、肥胖和女性性别之间先前存在的关联。

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本文引用的文献

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Aspirin prevention of cholesterol gallstone formation in prairie dogs.阿司匹林对草原犬鼠胆固醇性胆结石形成的预防作用
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A randomized, controlled trial of aspirin in persons recovered from myocardial infarction.一项针对心肌梗死康复者使用阿司匹林的随机对照试验。
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Arachidonic acid stimulates mucin secretion in prairie dog gallbladder.
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The epidemiology of gallbladder disease: observations in the Framingham Study.胆囊疾病的流行病学：弗明汉姆研究中的观察结果。
J Chronic Dis. 1966 Mar;19(3):273-92. doi: 10.1016/0021-9681(66)90132-9.
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Effect of vegetarianism on development of gall stones in women.素食主义对女性胆结石形成的影响。
Br Med J (Clin Res Ed). 1985 Jul 6;291(6487):11-2. doi: 10.1136/bmj.291.6487.11.
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A population study on the prevalence of gallstone disease: the Sirmione Study.一项关于胆结石疾病患病率的人群研究：西尔米奥内研究。
Hepatology. 1987 Sep-Oct;7(5):913-7. doi: 10.1002/hep.1840070520.
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Am Heart J. 1987 Jun;113(6):1356-64. doi: 10.1016/0002-8703(87)90648-x.