Mazzoleni G, deSa D, Gately J, Riddell R H
McMaster University Medical Centre, Hamilton, Ontario, Canada.
Dig Dis Sci. 1991 Aug;36(8):1154-60. doi: 10.1007/BF01297465.
Despite the frequency of gastrointestinal disease caused by Yersinia enterocolitica, intestinal perforation is a rare complication of this infection and to date only eight cases have been reported in the English literature. We describe a case of this unusual condition in a 17-year-old male patient with thalassemia intermedia requiring transfusion, who was also taking deferoxamine. The severity of the clinical picture is probably due to the increased virulence of Yersinia enterocolitica in the presence of deferoxamine and iron.
尽管小肠结肠炎耶尔森菌引起的胃肠道疾病很常见，但肠穿孔是这种感染的一种罕见并发症，迄今为止英文文献中仅报道过8例。我们描述了一名17岁中间型地中海贫血男性患者的这种罕见情况，该患者需要输血，同时正在服用去铁胺。临床表现的严重性可能是由于在去铁胺和铁存在的情况下小肠结肠炎耶尔森菌的毒力增加所致。
