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印度半城市高血清阳性人群中的先天性巨细胞病毒感染

Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India.

作者信息

Dar Lalit, Pati Sunil Kumar, Patro A Raj Kumar, Deorari Ashok Kumar, Rai Sanjay, Kant Shashi, Broor Shobha, Fowler Karen B, Britt William J, Boppana Suresh B

机构信息

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Pediatr Infect Dis J. 2008 Sep;27(9):841-3. doi: 10.1097/INF.0b013e3181723d55.

DOI:10.1097/INF.0b013e3181723d55
PMID:18645544
Abstract

To determine the incidence and natural history of congenital cytomegalovirus (CMV) infection in a population of women with near universal serologic reactivity for CMV, a prospective study of 423 women attending the antenatal clinic of the Comprehensive Rural Health Center in northern India was conducted. All 9 (2.1%) CMV positive infants were born to mothers who were CMV seropositive at the first antenatal visit. One child had hepatosplenomegaly at birth and another child had mild unilateral hearing loss at 4 months of age.

摘要

为了确定在巨细胞病毒(CMV)血清学反应几乎普遍存在的女性人群中先天性巨细胞病毒感染的发病率和自然病程,对印度北部综合农村健康中心产前诊所的423名女性进行了一项前瞻性研究。所有9名(2.1%)CMV阳性婴儿的母亲在首次产前检查时CMV血清学呈阳性。一名婴儿出生时患有肝脾肿大,另一名婴儿在4个月大时患有轻度单侧听力损失。

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