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种火鸡的实验性鼻气管炎(TRT)感染以及使用减毒活疫苗和灭活TRT疫苗预防其临床症状

An experimental turkey rhinotracheitis (TRT) infection in breeding turkeys and the prevention of its clinical effects using live-attenuated and inactivated TRT vaccines.

作者信息

Cook J K, Orthel F, Orbell S, Woods M A, Huggins M B

机构信息

Intervet UK, The Elms, The Thicket, Houghton, Huntingdon, Cambridgeshire, PE17 2BQ, UK.

出版信息

Avian Pathol. 1996 Jun;25(2):231-43. doi: 10.1080/03079459608419138.

DOI:10.1080/03079459608419138
PMID:18645855
Abstract

The experimental inoculation of 38-week-old turkey hens with a pool of field isolates of turkey rhinotracheitis virus (TRTV) induced a marked respiratory infection and a substantial drop in egg production. Administration of a live-attenuated TRT vaccine at 1 week of age did not protect the layers against respiratory infection, but provided good protection against the effects of challenge on laying performance. However, a combination of live priming followed by injection of inactivated vaccine provided excellent protection against both respiratory infection and drops in egg production.

摘要

用一组火鸡鼻气管炎病毒(TRTV)的田间分离株对38周龄的母火鸡进行实验性接种,引发了明显的呼吸道感染,并导致产蛋量大幅下降。1周龄时接种减毒活TRT疫苗并不能保护蛋鸡免受呼吸道感染,但能很好地保护其产蛋性能免受攻毒影响。然而,先接种活疫苗再注射灭活疫苗的联合免疫方案能为蛋鸡提供极佳的保护,使其既不发生呼吸道感染,产蛋量也不下降。

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