Bhandari Meghana S, Mazumder Amitabha, Jagannath Sundar, Vesole David H
St Vincent's Comprehensive Cancer Center, New York, NY 10011, USA.
Clin Lymphoma Myeloma. 2008 Jun;8(3):188-90. doi: 10.3816/CLM.2008.n.025.
Multiple malignancies in the same patient are unusual. This is particularly true for patients with hematologic malignancies who have a concomitant solid tumor. We report the unexpectedly higher frequency of renal cell carcinoma (RCC) associated with plasma cell dyscrasias. We report 6 cases of RCC in our institutional database of 600 patients with plasma cell dyscrasias over the past 10 years. We discuss the possible mechanisms that predisposed these patients to a secondary malignancy.
同一患者发生多种恶性肿瘤的情况并不常见。对于患有血液系统恶性肿瘤且同时伴有实体瘤的患者而言尤其如此。我们报告了肾细胞癌（RCC）与浆细胞异常增生相关的意外高发生率。在我们机构过去10年的600例浆细胞异常增生患者的数据库中，我们报告了6例肾细胞癌病例。我们讨论了使这些患者易患继发性恶性肿瘤的可能机制。
