Ben-Noun Liubov Louba, Laor Arie
Ben-Gurion University of the Negev, Soroka Hospital Medical Center, Faculty of Health Sciences, Beer-Sheva.
Exp Clin Cardiol. 2006 Spring;11(1):14-20.
Neck circumference (NC) is a simple screening measure for identifying overweight and obese patients. The main aim of the present study was to determine the relationship between changes in NC and changes in cardiovascular risk factors by evaluating some components of the metabolic syndrome.
The present longitudinal cohort study included 364 subjects (155 men and 209 women) with no known major medical conditions and who were not receiving any medication. Main indicators included NC, waist circumference, waist-to-hip ratio, body mass index, and fasting lipoprotein, glucose and uric acid levels.
Pearson's correlation coefficients indicated a significant association between changes in NC and changes in body mass index (men, r=0.67; women, r=0.69; each, P<0.0001), waist circumference (men, r=0.69; women, r=0.56; each, P<0.0001), waist-to-hip ratio (men, r=0.27; women, r=0.33; each, P<0.0001), and total cholesterol (men, r=0.68; women, r=0.64; each, P<0.0001), low density lipoprotein cholesterol (men, r=0.58; women, r=0.59; each, P<0.0001), triglyceride (men, r=0.48; women, r=0.44; each, P<0.0001), glucose (men, r=0.51; women, r=0.44; each, P<0.0001) and uric acid (men, r=0.42; women, r=0.47; each, P<0.0001) levels. The relative changes in NC contributed to independent significant changes in total cholesterol (8% for men and 1% for women), low density lipoprotein cholesterol (1% for men and 1% for women) and triglycerides (23% for men); it did not significantly contribute to changes in high density lipoprotein cholesterol, glucose or uric acid levels.
Changes in NC are positively correlated with changes in some factors of the metabolic syndrome and, therefore, are correlated with changes in the risk of cardiovascular disease.
颈围（NC）是识别超重和肥胖患者的一种简单筛查指标。本研究的主要目的是通过评估代谢综合征的一些组成部分，确定颈围变化与心血管危险因素变化之间的关系。
本纵向队列研究纳入了364名无已知重大疾病且未接受任何药物治疗的受试者（155名男性和209名女性）。主要指标包括颈围、腰围、腰臀比、体重指数以及空腹脂蛋白、血糖和尿酸水平。
Pearson相关系数表明，颈围变化与体重指数变化（男性，r = 0.67；女性，r = 0.69；均P < 0.0001）、腰围变化（男性，r = 0.69；女性，r = 0.56；均P < 0.0001）、腰臀比变化（男性，r = 0.27；女性，r = 0.33；均P < 0.0001）、总胆固醇变化（男性，r = 0.68；女性，r = 0.64；均P < 0.0001）、低密度脂蛋白胆固醇变化（男性，r = 0.58；女性，r = 0.59；均P < 0.0001）、甘油三酯变化（男性，r = 0.48；女性，r = 0.44；均P < 0.0001）、血糖变化（男性，r = 0.51；女性，r = 0.44；均P < 0.0001）和尿酸变化（男性，r = 0.42；女性，r = 0.47；均P < 0.0001）之间存在显著关联。颈围的相对变化导致总胆固醇（男性为8%，女性为1%）以及低密度脂蛋白胆固醇（男性为1%，女性为1%）和甘油三酯（男性为23%）出现独立的显著变化；对高密度脂蛋白胆固醇、血糖或尿酸水平的变化没有显著影响。
颈围变化与代谢综合征的某些因素变化呈正相关，因此与心血管疾病风险变化相关。
