Fiore Elisabetta, Rizzi Mattia, Ragazzi Monica, Vanoni Federica, Bernasconi Mara, Bianchetti Mario G, Simonetti Giacomo D
Department of Pediatrics Mendrisio and Bellinzona and the University of Bern, Bern University Hospital, Bern, Switzerland.
J Am Acad Dermatol. 2008 Oct;59(4):684-95. doi: 10.1016/j.jaad.2008.06.005. Epub 2008 Jul 24.
Acute hemorrhagic edema is an uncommon leukocytoclastic small-vessel vasculitis of young children.
To determine clinical features and outcome of acute hemorrhagic edema of young children.
Seven new cases are reported. A search of the literature revealed 287 published cases.
The 294 children (boys, 67%) ranged in age between 2 and 60 months (median, 11 months) and were in good general condition. In 195 children the disease developed after a simple acute infection. The exanthemata included large, round, red to purpuric plaques predominantly over the cheeks, ears, and extremities and mostly tender edema of the distal extremities, ears, and face. Involvement of body systems other than skin was rare. The children recovered spontaneously without sequelae.
Results of this review must be viewed with an understanding of the limitations of the analysis process, which incorporated data exclusively from single case reports or case series.
Acute hemorrhagic edema of young children is a very benign vasculitis. Physicians might rapidly develop the skills necessary to diagnose this condition.
急性出血性水肿是一种在幼儿中罕见的白细胞破碎性小血管血管炎。
确定幼儿急性出血性水肿的临床特征及预后。
报告7例新病例。检索文献发现287例已发表病例。
294例儿童（67%为男孩）年龄在2至60个月之间（中位数为11个月），一般状况良好。195例儿童在简单的急性感染后发病。皮疹包括主要分布在脸颊、耳部和四肢的大的、圆形的、红色至紫癜性斑块，以及大多累及远端肢体、耳部和面部的压痛性水肿。皮肤以外的身体系统受累罕见。患儿均自发恢复，无后遗症。
本综述的结果必须结合分析过程的局限性来看待，该分析仅纳入了来自单病例报告或病例系列的数据。
幼儿急性出血性水肿是一种非常良性的血管炎。医生可能会迅速掌握诊断该病所需的技能。
