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Binding of botulinum neurotoxin to the synaptosome fraction of rat brain.

作者信息

Kitamura M

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1976 Nov;295(2):171-5. doi: 10.1007/BF00499451.

Abstract

The radioactive 125I-labelled neurotoxin of C. botulinum type A, when incubated with rat brain homogenate, is bound selectively to the synaptosome fraction. Intact toxin was liberated from the synaptosome fraction by treatment with Triton X-100, SDS, trypsin or neuraminidase.

摘要

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