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Binding of botulinum neurotoxin to the synaptosome fraction of rat brain.

作者信息

Kitamura M

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1976 Nov;295(2):171-5. doi: 10.1007/BF00499451.

DOI:10.1007/BF00499451
PMID:186722
Abstract

The radioactive 125I-labelled neurotoxin of C. botulinum type A, when incubated with rat brain homogenate, is bound selectively to the synaptosome fraction. Intact toxin was liberated from the synaptosome fraction by treatment with Triton X-100, SDS, trypsin or neuraminidase.

摘要

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Binding of botulinum neurotoxin to the synaptosome fraction of rat brain.
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引用本文的文献

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本文引用的文献

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The action of botulinum toxin on the neuro-muscular junction.肉毒杆菌毒素对神经肌肉接头的作用。
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BOTULINUM TOXIN, TYPE A: EFFECTS ON CENTRAL NERVOUS SYSTEM.A型肉毒杆菌毒素：对中枢神经系统的影响
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梭菌神经毒素的受体与底物相互作用
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Infect Immun. 1989 Jan;57(1):272-7. doi: 10.1128/iai.57.1.272-277.1989.
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The isolation and characterization of acetylcholine-containing particles from brain.从大脑中分离和鉴定含乙酰胆碱的颗粒。
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An intracellular study of the action of repetitive nerve volleys and of botulinum toxin on miniature end-plate potentials.关于重复神经冲动和肉毒杆菌毒素对微小终板电位作用的细胞内研究。
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Chromatographic fractionation of the crystalline toxin of Clostridium botulinum type A.A型肉毒杆菌结晶毒素的色谱分离
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Significance of 12S toxin of Clostridium botulinum type E.E型肉毒梭菌12S毒素的意义
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Isolation and structural studies on synaptic complexes from rat brain.大鼠脑突触复合体的分离与结构研究。
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Highly purified synaptosomal membranes from rat brain. Preparation and characterization.
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Action of triton X-100 on ultrastructure and membrane-bound- enzymes of isolated nerve endings from rat brain.曲拉通X-100对大鼠脑分离神经末梢超微结构及膜结合酶的作用
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