Division of Child health, Sultan Qaboos University Hospital, Muscat, Oman.
Pediatr Rheumatol Online J. 2008 Aug 3;6:13. doi: 10.1186/1546-0096-6-13.
We report a case of Wegener's Granulomatosis (WG) associated with blastomycosis. This appears to be the first case report of WG co-existing with a tissue proven blastomycosis infection. The temporal correlation of the two conditions suggests that blastomycosis infection (and therefore possibly other fungal infections), may trigger the systemic granulomatous vasculitis in a predisposed individual; a provocative supposition warranting further study.
我们报告了一例韦格纳肉芽肿(WG)合并球孢子菌病的病例。这似乎是首例WG 与组织证实的球孢子菌感染共存的病例报告。这两种情况的时间相关性表明,球孢子菌感染(因此可能还有其他真菌感染)可能在易感个体中引发全身性肉芽肿性血管炎;这一推测性假设值得进一步研究。