4-Hydroxynonenal-modified Ro 60 autoantigen accelerates autoimmunity in experimental animals.
作者信息
Kurien B T, Scofield R H
出版信息
Rheumatology (Oxford). 2008 Oct;47(10):1587. doi: 10.1093/rheumatology/ken300. Epub 2008 Aug 2.
Abstract
摘要
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Rheumatology (Oxford). 2008 Oct;47(10):1587. doi: 10.1093/rheumatology/ken300. Epub 2008 Aug 2.
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本文引用的文献
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Consequence of neo-antigenicity of the 'altered self'.“改变的自身”的新抗原性的后果。
Rheumatology (Oxford). 2008 May;47(5):567-71. doi: 10.1093/rheumatology/ken014. Epub 2008 Mar 3.
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Oxidatively modified autoantigens in autoimmune diseases.自身免疫性疾病中的氧化修饰自身抗原。
Free Radic Biol Med. 2006 Aug 15;41(4):549-56. doi: 10.1016/j.freeradbiomed.2006.05.020. Epub 2006 May 23.
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Lipid peroxidation in systemic lupus erythematosus.系统性红斑狼疮中的脂质过氧化作用。
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4
Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading.狼疮相关的60 kDa Ro蛋白与脂质氧化产物4-羟基-2-壬烯醛发生修饰后，会增加抗原性并促进表位扩展。
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Free radical mediated peroxidative damage in systemic lupus erythematosus.系统性红斑狼疮中自由基介导的过氧化损伤
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Increased levels of 4-hydroxynonenal modified proteins in plasma of children with autoimmune diseases.自身免疫性疾病患儿血浆中4-羟基壬烯醛修饰蛋白水平升高。
Free Radic Biol Med. 1997;23(3):357-60. doi: 10.1016/s0891-5849(96)00586-2.
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Increased lipid peroxidation in children with autoimmune diseases.自身免疫性疾病患儿脂质过氧化增加。
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8
A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors.60-kD Ro自身抗原在缺陷型5S rRNA前体的一条废弃途径中的可能作用。
Genes Dev. 1994 Dec 1;8(23):2891-903. doi: 10.1101/gad.8.23.2891.
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