Galacteros F, Guilloud-Bataille M, Feingold J
INSERM U91, Henri Mondor Hospital, Créteil, France.
Blood. 1991 Aug 15;78(4):1121-4.
We have measured by cation exchange high pressure liquid chromatography adult hemoglobin (HbA) concentration at birth in 6,123 unselected single newborn individuals. Probably because of the high precision of the analytical method used, we could demonstrate clear a relationship between HbA concentration and, respectively, gestational age and birth weight. We also demonstrated a significant difference in the Hb switching process between male and female newborns. Reference percentile distribution curves are given that could be used to define more precisely those children having slow or fast Hb switching.
我们采用阳离子交换高压液相色谱法测定了6123名未经筛选的单胎新生儿出生时的成人血红蛋白（HbA）浓度。可能是由于所用分析方法的高精度，我们能够明确证明HbA浓度与胎龄和出生体重之间的关系。我们还证明了男、女新生儿在血红蛋白转换过程中存在显著差异。给出了参考百分位数分布曲线，可用于更精确地界定那些血红蛋白转换缓慢或快速的儿童。
