面肩肱型肌营养不良症、强直性肌营养不良症和遗传性运动感觉神经病I型患者的不同类型疲劳。体验性疲劳和生理性疲劳。
Different types of fatigue in patients with facioscapulohumeral dystrophy, myotonic dystrophy and HMSN-I. Experienced fatigue and physiological fatigue.
作者信息
Kalkman Joke S, Zwarts Machiel J, Schillings Maartje L, van Engelen Baziel G M, Bleijenberg Gijs
机构信息
Department of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
出版信息
Neurol Sci. 2008 Sep;29 Suppl 2:S238-40. doi: 10.1007/s10072-008-0949-7.
Although fatigue is a common symptom in neuromuscular disorders, little is known about different types of fatigue. Sixty-five FSHD, 79 adult-onset MD and 73 HMSN type I patients were studied. Experienced fatigue was assessed with the CIS-fatigue subscale. Physiological fatigue was measured during a 2-min sustained maximal voluntary contraction of the biceps brachii muscle using the twitch interpolation technique to assess central activation failure (CAF) and peripheral fatigue. Experienced fatigue, CAF and peripheral fatigue appeared to be predominantly separate types of fatigue.
尽管疲劳是神经肌肉疾病的常见症状，但对于不同类型的疲劳却知之甚少。对65例面肩肱型肌营养不良症（FSHD）患者、79例成人起病型肌营养不良症（MD）患者和73例I型遗传性运动感觉神经病（HMSN）患者进行了研究。使用CIS-疲劳分量表评估主观疲劳。采用抽搐插值技术，在肱二头肌持续2分钟的最大自主收缩过程中测量生理疲劳，以评估中枢激活失败（CAF）和外周疲劳。主观疲劳、CAF和外周疲劳似乎主要是不同类型的疲劳。
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