Ashutosh K, Keighley J F
Thorax. 1976 Oct;31(5):552-7. doi: 10.1136/thx.31.5.552.
Serum angiotensin converting enzyme (ACE) activity was measured in 10 patients with early active sarcoidosis, nine patients with inactive or resolving sarcoidosis, 10 patients with malignant pulmonary neoplasms, eight patients with miscellaneous lung diseases, and 18 control subjects with no known pulmonary disease. The serum ACE activity, expressed in units/ml, in control subjects (5-88 +/- 1-84), was no different from the values obtained in patients with inactive or resolving sarcoidosis (6-85 +/- 2-48) or miscellaneous lung diseases (4-61 +/- 3-20). However, the ACE activity was found to be markedly raised in patients with early active sarcoidosis (13-49 +/- 2-52), and there was no overlap with control values. The patients with pulmonary neoplasms had significantly lower values of serum ACE activity than the control subjects (2-80 +/- 3-30).
对10例早期活动性结节病患者、9例非活动性或正在缓解的结节病患者、10例肺恶性肿瘤患者、8例其他肺部疾病患者以及18例无已知肺部疾病的对照者测定了血清血管紧张素转换酶（ACE）活性。对照者的血清ACE活性以单位/毫升表示（5 - 88±1 - 84），与非活动性或正在缓解的结节病患者（6 - 85±2 - 48）或其他肺部疾病患者（4 - 61±3 - 20）所测得的值无差异。然而，发现早期活动性结节病患者的ACE活性显著升高（13 - 49±2 - 52），且与对照值无重叠。肺肿瘤患者的血清ACE活性值显著低于对照者（2 - 80±3 - 30）。
