Kita M, Mandala E, Saratzis A, Ventzi L, Venizelos I, Keryttopoulos P, Efstathiadou Z, Garyfallos A, Avramides A
Department of Endocrinology, Hippocratic General Hospital, Thessaloniki, Greece.
Exp Clin Endocrinol Diabetes. 2008 Jun;116(6):363-5. doi: 10.1055/s-2008-1042402.
Primary Adrenal Lymphoma (PAL) is a very rare clinical entity. Adrenal insufficiency is a common complication of this pathology. Most patients present with clinical and laboratory findings of adrenal insufficiency and bilateral enlargement of the adrenal glands. We present a 78-year-old woman admitted to our institution with typical clinical and laboratory findings of adrenal insufficiency. Computerized tomography (CT) of the abdomen revealed bilateral enlargement of the adrenal glands. The patient was eventually diagnosed with a diffuse large B-cell lymphoma after a CT-guided needle adrenal biopsy and treated with combined immuno-chemotherapy (R-LPD-COP). Twenty months after the initial evaluation, she is in good condition, with no signs of adrenal insufficiency.
原发性肾上腺淋巴瘤（PAL）是一种非常罕见的临床病症。肾上腺功能不全是这种病症的常见并发症。大多数患者表现出肾上腺功能不全以及肾上腺双侧肿大的临床和实验室检查结果。我们报告一位78岁女性，因典型的肾上腺功能不全临床和实验室检查结果入住我院。腹部计算机断层扫描（CT）显示肾上腺双侧肿大。经CT引导下肾上腺穿刺活检，该患者最终被诊断为弥漫性大B细胞淋巴瘤，并接受了联合免疫化疗（R-LPD-COP）。初始评估20个月后，她状况良好，无肾上腺功能不全迹象。
