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疑似气道阻塞的基层医疗人群中的诊断确定性、合并症和用药情况:DIDASCO2研究

Diagnostic certainty, co-morbidity and medication in a primary care population with presumed airway obstruction: the DIDASCO2 study.

作者信息

Buffels Johan, Degryse Jan, Liistro Giuseppe

机构信息

Department of General Practice, K.U.Leuven, Leuven, Belgium.

出版信息

Prim Care Respir J. 2009 Mar;18(1):34-40. doi: 10.3132/pcrj.2008.00047.

Abstract

STUDY OBJECTIVES

To document the rate of diagnostic certainty, co-morbidity and use of medication in patients with presumed obstructive airway disease (OAD) in a primary care setting.

METHODS

Twenty-six general practitioners (GPs) were asked to select the last 50 contacts with patients older than 40 years of age who were taking bronchodilators and/or inhaled corticosteroids or who had known OAD. After reviewing their medical data on file, the GPs gave their diagnostic opinion and rated their certainty about the diagnosis using a Likert-type scale.

RESULTS

Analysis of 1126 files revealed that in at least 523 patients (46.4%), a diagnostic work-up was judged necessary. The GPs judged that 6% of the patients had no OAD. Less than 33% of the study population underwent spirometry during the two years preceding the survey. The number of co-morbid conditions was on average 2.2 for patients with asthma and 3.2 for patients with COPD. Patients with presumed COPD took significantly more drugs (mean, 5.1; 95% CI, 4.8-5.3) than did patients with other diagnostic labels (mean, 4.6 95%; CI, 4.4-4.8).

CONCLUSIONS

We confirmed the underuse of spirometry as a diagnostic tool in presumed airway obstruction in primary care. Nearly half of the patients older than 40 years who were taking bronchodilators and/or inhaled corticosteroids needed a diagnostic work-up. This population had a high prevalence of co-morbidity and polypharmacy.

摘要

研究目的

记录在初级保健机构中,疑似阻塞性气道疾病(OAD)患者的诊断确定性、合并症情况及药物使用情况。

方法

邀请26名全科医生(GP)挑选出他们最近接触的50名40岁以上正在使用支气管扩张剂和/或吸入性糖皮质激素或已知患有OAD的患者。在查阅这些患者的病历档案后,全科医生给出他们的诊断意见,并使用李克特量表对诊断的确定性进行评分。

结果

对1126份档案的分析显示,至少523名患者(46.4%)被认为需要进行诊断性检查。全科医生判断6%的患者没有患OAD。在调查前两年内,不到33%的研究人群接受了肺活量测定。哮喘患者的合并症平均数量为2.2种,慢性阻塞性肺疾病(COPD)患者为3.2种。疑似COPD患者服用的药物明显多于其他诊断类型的患者(平均为5.1种;95%置信区间为4.8 - 5.3),其他诊断类型患者平均服用4.6种药物(95%置信区间为4.4 - 4.8)。

结论

我们证实了在初级保健中,肺活量测定作为疑似气道阻塞诊断工具的使用不足。近一半正在使用支气管扩张剂和/或吸入性糖皮质激素的40岁以上患者需要进行诊断性检查。该人群合并症和多种药物联用的患病率较高。

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