Maruko I, Iida T, Sekiryu T, Fujiwara T
Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Br J Ophthalmol. 2008 Nov;92(11):1488-91. doi: 10.1136/bjo.2007.131409. Epub 2008 Aug 14.
To report early morphological changes and functional abnormalities in group 2A idiopathic juxtafoveolar retinal telangiectasis (IJRT) using spectral domain optical coherence tomography (SD-OCT) and microperimetry.
Six eyes (three patients; average age, 64 years) with group 2A IJRT were examined using SD-OCT and microperimetry.
On SD-OCT, breaks in the highly reflective line, considered the boundary between the photoreceptor inner and outer segments, at the temporal to the fovea and corresponding to the telangiectasis lesions were observed in all eyes. Highly reflective tissue was observed in the outer retinal layer in five eyes. In three eyes with a right-angle venule, the outer retinal layer was replaced by the highly reflective tissue and was contiguous to the inner retinal layer. Microperimetry showed the reduction in the retinal sensitivity thresholds at the temporal to the fovea in five eyes.
Early morphological alterations in group 2A IJRT in SD-OCT were observed. These finding might be visualisation of Müller cell abnormality on SD-OCT. At the same time, the disorder of photoreceptors occurs at the telangiectasis lesions from MP-1. Detailed observation of these abnormalities provides an understanding of the morphological and functional features of group 2A IJRT.
利用频域光学相干断层扫描（SD - OCT）和微视野计报告2A型特发性黄斑旁视网膜毛细血管扩张症（IJRT）的早期形态学变化和功能异常。
对6只眼（3例患者；平均年龄64岁）的2A型IJRT进行SD - OCT和微视野计检查。
在SD - OCT上，所有眼中均观察到在黄斑颞侧、对应毛细血管扩张病变处，被认为是光感受器内外节之间边界的高反射线中断。5只眼中在外视网膜层观察到高反射组织。在3只伴有直角小静脉的眼中，外视网膜层被高反射组织取代并与内视网膜层相邻。微视野计显示5只眼在黄斑颞侧的视网膜敏感度阈值降低。
观察到2A型IJRT在SD - OCT上的早期形态学改变。这些发现可能是SD - OCT上 Müller细胞异常的表现。同时，从微视野计1（MP - 1）来看，光感受器的紊乱发生在毛细血管扩张病变处。对这些异常的详细观察有助于了解2A型IJRT的形态学和功能特征。
