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放射治疗计划的体积和剂量学评估:放射适形指数

Volumetric and dosimetric evaluation of radiation treatment plans: radiation conformity index.

作者信息

Knöös T, Kristensen I, Nilsson P

机构信息

Department of Radiation Physics, Lund University Hospital, Sweden.

出版信息

Int J Radiat Oncol Biol Phys. 1998 Dec 1;42(5):1169-76. doi: 10.1016/s0360-3016(98)00239-9.

Abstract

PURPOSE

The use of conformal radiation therapy has grown substantially during the last years since three-dimensional (3D) treatment planning systems with beams-eye-view planning has become commercially available. We studied the degree of conformity reached in clinical routines for some common diagnoses treated at our department by calculating a radiation conformity index (RCI).

METHODS AND MATERIALS

The radiation conformity index, determined as the ratio between the target volume (PTV) and the irradiated volume, has been evaluated for 57 patients treated with 3D treatment plans.

RESULTS AND CONCLUSION

The RCI was found to vary from 0.3 to 0.6 (average 0.4), a surprisingly low figure. The higher RCI is typical for pelvic treatments (e.g., prostate) and stereotactic treatments. The lower RCI is found for extended tumors, such as mammary carcinomas where the adjacent nodes are included. The latter is also valid for most lung cancer patients studied. The RCI gives a consistent method for quantifying the degree of conformity based on isodose surfaces and volumes. Care during interpretation of RCI must always be taken, since small changes in the minimum dose can dramatically change the treated volume.

摘要

目的

自从具有射野方向观(BEV)计划的三维(3D)治疗计划系统商业化以来,适形放射治疗在过去几年中得到了显著发展。我们通过计算放射适形指数(RCI),研究了在我们科室治疗的一些常见疾病的临床常规中所达到的适形程度。

方法和材料

对57例采用3D治疗计划治疗的患者评估了放射适形指数,该指数定义为靶区体积(PTV)与受照体积之比。

结果与结论

发现RCI在0.3至0.6之间变化(平均0.4),这一数字低得出奇。较高的RCI典型见于盆腔治疗(如前列腺癌)和立体定向治疗。较低的RCI见于范围较大的肿瘤,如包含邻近淋巴结的乳腺癌。这对于大多数所研究的肺癌患者也同样适用。RCI提供了一种基于等剂量面和体积来量化适形程度的一致方法。解读RCI时必须始终谨慎,因为最小剂量的微小变化可能会显著改变受照体积。

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