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吉田实体瘤发育过程中变化的电子自旋共振研究。I:抗坏血酸自由基。

Electron spin resonance study of changes during development of solid Yoshida tumour. I: Ascorbyl radical.

作者信息

Silcock J M, Dodd N J

出版信息

Br J Cancer. 1976 Nov;34(5):550-5. doi: 10.1038/bjc.1976.210.

Abstract

The ascorbyl radical concentration has been observed, by means of electron spin resonance spectroscopy, in the blood and spleen of female Wistar rats carrying a Yoshida tumour. The ascorbyl radical concentration of the tumour tissue itself was studied as the tumour was developing, and as it was regressing after treatment with methylene dimethane sulphonate. Changes in the concentration of this radical may be related to host tumour reactions.

摘要

通过电子自旋共振光谱法,观察了携带吉田肿瘤的雌性Wistar大鼠血液和脾脏中抗坏血酸自由基的浓度。在肿瘤发展过程中以及在用亚甲基二甲磺酸盐治疗后肿瘤消退时,对肿瘤组织本身的抗坏血酸自由基浓度进行了研究。该自由基浓度的变化可能与宿主肿瘤反应有关。

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