Ata Yaser M, Ahmed Mohamed B, Al-Mohannadi Fatima S, Al-Jassim Fatima A, Shabbir Azhar
Urology Department, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
Plastic Surgery Department, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
J Surg Case Rep. 2023 Apr 28;2023(4):rjad224. doi: 10.1093/jscr/rjad224. eCollection 2023 Apr.
Nicolau syndrome (NS), also referred as embolia cutis medicamentosa and livedo-like dermatitis, is an uncommon complication followed by drugs administered intramuscularly, intraarticularly or subcutaneously. In this case report we present a case of a 65-year-old lady who had a single dose of diclofenac sodium as an intramuscular injection in her left buttock due to back pain that led to developing what known as NS. She was treated with surgical debridement, drain insertion and skin approximation with antibiotics for 2 weeks with daily sterile dressing. The wound healed completely with scarring. NS is a preventable outcome, thus, proper procedures and precautions should be taken during intramuscular medication administration. Healthcare providers should avoid unnecessary injections, be familiar with the complication and consider it as a potential diagnosis for severe localized pain after any injection.
尼科劳综合征（NS），也被称为药物性皮肤栓塞和类青斑样皮炎，是一种不常见的并发症，常继发于肌肉内、关节内或皮下给药之后。在本病例报告中，我们呈现了一名65岁女性的病例，她因背痛在左臀部单次肌肉注射双氯芬酸钠后，患上了尼科劳综合征。她接受了手术清创、引流管插入，并使用抗生素进行了为期2周的皮肤缝合，同时每天进行无菌换药。伤口完全愈合，留有瘢痕。尼科劳综合征是一种可预防的结果，因此，在进行肌肉注射给药时应采取适当的操作程序和预防措施。医护人员应避免不必要的注射，熟悉该并发症，并将其视为任何注射后严重局部疼痛的潜在诊断。
