Francès C, Boisnic S, Hartmann D J, Dautzenberg B, Branchet M C, Charpentier Y L, Robert L
Department of Internal Medicine, Hôpital le Pitié, Paris, France.
Br J Dermatol. 1991 Jul;125(1):43-7. doi: 10.1111/j.1365-2133.1991.tb06037.x.
Biopsies were taken from the upper and inner arm of 10 60-year-old male cigarette smokers and compared with 10 age-matched controls who were non-smokers. The mean relative area, number and thickness of the elastic fibres were significantly increased in the cigarette smokers compared to the controls. These results were confirmed using antibodies to elastin or the microfibrillar component of elastic tissue. In the smokers the broader and more fragmented elastic fibres in the skin were not as intensely stained as those of the non-smokers and the ultrastructural alterations of the elastic fibres were similar to those in solar elastosis.
对10名60岁男性吸烟者的上臂和内臂进行活检，并与10名年龄匹配的非吸烟对照者进行比较。与对照组相比，吸烟者弹性纤维的平均相对面积、数量和厚度显著增加。使用针对弹性蛋白或弹性组织微纤维成分的抗体证实了这些结果。在吸烟者中，皮肤中更宽且更破碎的弹性纤维染色不如非吸烟者强烈，并且弹性纤维的超微结构改变与日光性弹力纤维变性中的相似。
