Farmakis Dimitrios, Filippatos Gerasimos, Parissis John, Kremastinos Dimitrios Th, Gheorghiade Mihai
Second Department of Cardiology, Heart Failure Unit, Attikon University Hospital, Athens, Greece.
Heart Fail Rev. 2009 Jun;14(2):59-63. doi: 10.1007/s10741-008-9109-7. Epub 2008 Aug 29.
Hyponatremia is the most common electrolyte abnormality found in hospitalized patients with heart failure. It may occur in patients who have hypovolemic, hypervolemic, or euvolemic state. It is usually not corrected by available therapies. It is a major predictor of prognosis, and correction of hyponatremia can be effectively accomplished by vasopressin antagonists. However, it still remains to be seen whether the normalization of serum sodium with vasopressin antagonists will also lead to an improved long-term prognosis.
低钠血症是心力衰竭住院患者中最常见的电解质异常。它可能发生在低血容量、高血容量或血容量正常的患者中。现有治疗方法通常无法纠正这种情况。它是预后的主要预测指标，血管加压素拮抗剂可有效纠正低钠血症。然而，血管加压素拮抗剂使血清钠正常化是否也会改善长期预后仍有待观察。
