德国新种奇美拉分枝杆菌的发生及临床相关性
Occurrence and clinical relevance of Mycobacterium chimaera sp. nov., Germany.
作者信息
Schweickert Birgitta, Goldenberg Oliver, Richter Elvira, Göbel Ulf B, Petrich Annette, Buchholz Petra, Moter Annette
机构信息
Institut für Mikrobiologie und Hygiene, Charité-Universitätsmedizin, Berlin, Germany.
出版信息
Emerg Infect Dis. 2008 Sep;14(9):1443-6. doi: 10.3201/eid1409.071032.
Abstract
Retrospective molecular genetic analysis of 166 Mycobacterium intracellulare isolates showed that 143 (86%) strains could be assigned to Mycobacterium chimaera sp. nov. Of 97 patients from whom M. chimaera sp. nov. was isolated, only 3.3% exhibited mycobacterial lung disease, whereas all M. intracellulare isolates caused severe pulmonary infections.
摘要
对166株胞内分枝杆菌分离株进行的回顾性分子遗传学分析表明，143株（86%）菌株可归为新种马氏分枝杆菌。在分离出该新种马氏分枝杆菌的97例患者中，仅有3.3%表现为分枝杆菌性肺病，而所有胞内分枝杆菌分离株均引起严重肺部感染。
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