Butt Zubair M, Perlmutter Adam E, Piacente Pamela M, Wilding Gregory, Tan Wei, Kim Hyung L, Mohler James L, Guru Khurshid A
Department of Urologic Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
JSLS. 2008 Jul-Sep;12(3):241-5.
Obesity is a major comorbidity in the Western world and influences outcomes of patient care. A minimally invasive approach towards radical cystectomy has been increasing in popularity. We sought to determine the influence of body mass index (BMI) on robot-assisted radical cystectomy.
Fifty-one consecutive patients underwent robot-assisted radical cystectomy for bladder cancer from October 2005 to April 2007 and were categorized into 3 groups based on their weight: normal (BMI <25), overweight (BMI=25 to 29) and obese (BMI= 30 to 39.9). Effect of BMI on intraoperative, pathologic, and postoperative outcomes was assessed by retrospective review of the robot-assisted radical cystectomy database.
Mean BMI was 28.0, and 71% of the patients were overweight or obese. BMI did not correlate with age, sex, or American Society of Anesthesiologists (ASA) score. Overweight and obese patients had similar operative times and estimated blood loss compared with patients with normal BMI. Overweight and obese patients with bulky disease (pT3-4) had significantly higher rates of positive surgical margins (P=0.05). Complication rates were similar.
Robotic-assisted radical cystectomy can be considered for patients of all body mass indices. Wider excision should be performed in patients with higher BMI.
肥胖是西方世界主要的合并症,影响患者的治疗效果。根治性膀胱切除术的微创方法越来越受欢迎。我们试图确定体重指数(BMI)对机器人辅助根治性膀胱切除术的影响。
2005年10月至2007年4月,连续51例患者接受机器人辅助根治性膀胱切除术治疗膀胱癌,并根据体重分为3组:正常组(BMI<25)、超重组(BMI=25至29)和肥胖组(BMI=30至39.9)。通过回顾机器人辅助根治性膀胱切除术数据库,评估BMI对术中、病理和术后结果的影响。
平均BMI为28.0,71%的患者超重或肥胖。BMI与年龄、性别或美国麻醉医师协会(ASA)评分无关。与BMI正常的患者相比,超重和肥胖患者的手术时间和估计失血量相似。患有大块肿瘤(pT3-4)的超重和肥胖患者手术切缘阳性率显著更高(P=0.05)。并发症发生率相似。
所有体重指数的患者都可考虑行机器人辅助根治性膀胱切除术。BMI较高的患者应进行更广泛的切除。