Li Q, Kakizaki M, Kuriyama S, Sone T, Yan H, Nakaya N, Mastuda-Ohmori K, Tsuji I
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Br J Cancer. 2008 Oct 7;99(7):1179-84. doi: 10.1038/sj.bjc.6604645. Epub 2008 Sep 2.
We examined the risk of lung cancer in relation to green tea consumption in a population-based cohort study in Japan among 41,440 men and women, aged 40-79 years, who completed a questionnaire in 1994 regarding green tea consumption and other health-related lifestyle factors. During the follow-up period of 7 years (from 1995 to 2001), 302 cases of lung cancer were identified, and the Cox proportional hazards regression model was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs). The multivariable-adjusted HRs of lung cancer incidence for green tea consumption of 1 or 2, 3 or 4, and 5 or more cups/day as compared to less than 1 cup/day were 1.14 (95% CI: 0.80-1.62), 1.18 (95% CI: 0.83-1.66), and 1.17 (95% CI: 0.85-1.61), respectively (P for trend=0.48). This cohort study has found no evidence that green tea consumption is associated with lung cancer.
在日本一项基于人群的队列研究中,我们调查了41440名年龄在40至79岁之间的男性和女性饮用绿茶与患肺癌风险之间的关系,这些人于1994年完成了一份关于绿茶消费及其他与健康相关生活方式因素的问卷调查。在7年的随访期(1995年至2001年)内,共确诊302例肺癌病例,并使用Cox比例风险回归模型来估计风险比(HR)和95%置信区间(CI)。与每天饮用绿茶少于1杯相比,每天饮用1或2杯、3或4杯以及5杯及以上绿茶的肺癌发病多变量调整后HR分别为1.14(95%CI:0.80 - 1.62)、1.18(95%CI:0.83 - 1.66)和1.17(95%CI:0.85 - 1.61)(趋势P值 = 0.48)。这项队列研究未发现饮用绿茶与肺癌有关的证据。