慢性增生性口腔黏膜中“角蛋白池”的电子显微镜观察

Electron microscopic observations of "keratin pools" in chronic hyperplastic oral mucosa.

作者信息

Archard H O, Denys F R, Martinez M G

出版信息

J Oral Pathol. 1976 Nov;5(6):371-84. doi: 10.1111/j.1600-0714.1976.tb01788.x.

DOI:10.1111/j.1600-0714.1976.tb01788.x

Abstract

"Keratin pools," previously characterized clinically and histochemically in the superficial epithelium of chronic hyperplastic oral mucosa, were studied by light and electron microscopy. These occured as small beaded and larger coalescent masses which varied in metachromasia. Ultrastructurally, the "keratin pools" consisted of electron-dense, amorphous or finely-granular material developing and coalescing, chiefly as extracellular deposits. The "pools" frequently possessed a layered arrangement alternating with cells having distinct tonofilaments, desmosomes, and definite cell membranes. Occasional bands of filamentous-like material, possibly representing tonofilament bundles, were observed in some "pools."

摘要

“角蛋白池”先前已通过临床和组织化学方法在慢性增生性口腔黏膜的表层上皮中进行了表征，现通过光学显微镜和电子显微镜进行研究。这些“角蛋白池”表现为小的串珠状和较大的融合团块，异染性各异。超微结构上，“角蛋白池”由电子致密的无定形或细颗粒物质组成，这些物质主要作为细胞外沉积物形成并融合。“角蛋白池”通常具有分层结构，与具有明显张力丝、桥粒和明确细胞膜的细胞交替排列。在一些“角蛋白池”中偶尔观察到丝状物质带，可能代表张力丝束。