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The clinical significance of amenorrhea as a diagnostic criterion for anorexia nervosa.闭经作为神经性厌食症诊断标准的临床意义。
Int J Eat Disord. 2008 Sep;41(6):559-63. doi: 10.1002/eat.20534.
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Anorexia nervosa treatment: a systematic review of randomized controlled trials.神经性厌食症的治疗:随机对照试验的系统评价
Int J Eat Disord. 2007 May;40(4):310-20. doi: 10.1002/eat.20367.
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Plasma homocysteine levels in female patients with eating disorders.
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An attempt to understand the paradox of anorexia nervosa without drive for thinness.尝试理解无追求消瘦驱力的神经性厌食症悖论。
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Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study.口服避孕药(诺孕酯/炔雌醇)对神经性厌食症青春期女性骨密度的影响:一项双盲、安慰剂对照研究。
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How do children with eating disorders differ from adolescents with eating disorders at initial evaluation?患有饮食失调症的儿童在初次评估时与患有饮食失调症的青少年有何不同?
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Identifying dieters who will develop an eating disorder: a prospective, population-based study.识别可能会患上饮食失调症的节食者:一项基于人群的前瞻性研究。
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Diagnostic criteria for anorexia nervosa: looking ahead to DSM-V.神经性厌食症的诊断标准:展望《精神疾病诊断与统计手册》第五版。
Int J Eat Disord. 2005;37 Suppl:S95-7. doi: 10.1002/eat.20125.
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Three psychotherapies for anorexia nervosa: a randomized, controlled trial.三种治疗神经性厌食症的心理疗法:一项随机对照试验。
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The dearth of psychological treatment studies for anorexia nervosa.针对神经性厌食症的心理治疗研究匮乏。
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百分之八十五的什么?神经性厌食症体重临界值的差异对体重过轻的患病率有重大影响。

Eighty-five per cent of what? Discrepancies in the weight cut-off for anorexia nervosa substantially affect the prevalence of underweight.

作者信息

Thomas J J, Roberto C A, Brownell K D

机构信息

Department of Psychology, Yale University, New Haven, CT, USA.

出版信息

Psychol Med. 2009 May;39(5):833-43. doi: 10.1017/S0033291708004327. Epub 2008 Sep 8.

DOI:10.1017/S0033291708004327
PMID:18775087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2847836/
Abstract

BACKGROUND

DSM-IV cites <85% of expected body weight (EBW) as a guideline for the diagnosis of anorexia nervosa (AN) but does not require a specific method for calculating EBW. The purpose of the present study was to determine the degree to which weight cut-off calculations vary across studies, and to evaluate whether differential cut-offs lead to discrepancies in the prevalence of individuals who are eligible for the AN diagnosis.

METHOD

Two coders independently recorded the EBW calculation methods from 99 studies that either (a) compared individuals with AN to those with subclinical eating disorders or (b) conducted AN treatment trials. Each weight cut-off was applied to a nationally representative (n=12001) and treatment-seeking (n=189) sample to determine the impact of EBW calculation on the proportion who met the AN weight criterion.

RESULTS

Coders identified 10 different EBW methods, each of which produced different weight cut-offs for the diagnosis of AN. Although only 0.23% of the national sample met the lowest cut-off, this number increased 43-fold to 10.10% under the highest cut-off. Similarly, only 48.1% of treatment seekers met the lowest cut-off, whereas 89.4% met the highest.

CONCLUSIONS

There is considerable variance across studies in the determination of the AN weight cut-off. Discrepancies substantially affect the proportion of individuals who are eligible for diagnosis, treatment and insurance reimbursement. However, differences may not be fully appreciated because the ubiquitous citation of the 85% criterion creates a sense of false consensus.

摘要

背景

《精神疾病诊断与统计手册第四版》(DSM-IV)将预期体重(EBW)的<85%作为神经性厌食症(AN)诊断的指导标准,但未要求使用特定的EBW计算方法。本研究的目的是确定不同研究中体重截断值计算的差异程度,并评估不同的截断值是否会导致符合AN诊断标准的个体患病率出现差异。

方法

两名编码员独立记录了99项研究中的EBW计算方法,这些研究要么(a)将AN患者与亚临床饮食失调患者进行比较,要么(b)进行AN治疗试验。将每个体重截断值应用于一个具有全国代表性的样本(n = 12001)和一个寻求治疗的样本(n = 189),以确定EBW计算对符合AN体重标准的比例的影响。

结果

编码员识别出10种不同的EBW方法,每种方法在诊断AN时产生不同的体重截断值。尽管全国样本中只有0.23%的人符合最低截断值,但在最高截断值下,这一数字增加了43倍,达到10.10%。同样,寻求治疗者中只有48.1%的人符合最低截断值,而89.4%的人符合最高截断值。

结论

不同研究在确定AN体重截断值方面存在相当大的差异。这些差异极大地影响了符合诊断、治疗和保险报销条件的个体比例。然而,由于85%标准的普遍引用营造了一种错误共识感,这些差异可能未得到充分认识。